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Rabbit Protein Kinase C beta1 Polyclonal Antibody | anti-Prkcb antibody

Protein Kinase C beta1 (PKCb1)

Gene Names
Prkcb; Pkcb; Prkcb1
Reactivity
Human, Mammal, Mouse, Rat, Rodent
Applications
Western Blot
Purity
Serum
Serum
Synonyms
Protein Kinase C beta1; Polyclonal Antibody; Protein Kinase C beta1 (PKCb1); Anti -Protein Kinase C beta1 (PKCb1); anti-Prkcb antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mammal, Mouse, Rat, Rodent
Clonality
Polyclonal
Isotype
IgG
Specificity
Specifically reacts with protein kinase C beta1 from most mammalian species, including rodent (mouse/rat) and human.
Purity/Purification
Serum
Serum
Form/Format
Supplied as a liquid in PBS, 0.05% sodium azide.
Applicable Applications for anti-Prkcb antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Dilution: Western Blot (ECL): 1:1000. Decrease dilution of antibody if less senstive detecting system such as alkaline phosphatase is to be used.
Optimal dilutions to be determined by researcher.
Immunogen
KLH conjugated synthetic peptide corresponding to aa661-671 of Protein Kinase C beta1. Sequence: 661S-Y-T-N-P-E-F-V-I-N-V671. Molecular Weight: 76.9kD.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Product Categories/Family for anti-Prkcb antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
76,751 Da
NCBI Official Full Name
protein kinase C beta type isoform 2
NCBI Official Synonym Full Names
protein kinase C, beta
NCBI Official Symbol
Prkcb
NCBI Official Synonym Symbols
Pkcb; Prkcb1
NCBI Protein Information
protein kinase C beta type; PKC-beta; protein kinase C beta I; protein kinase C beta II; protein kinase C, beta 1
UniProt Protein Name
Protein kinase C beta type
Protein Family
UniProt Gene Name
Prkcb
UniProt Synonym Gene Names
Pkcb; Prkcb1; PKC-B; PKC-beta
UniProt Entry Name
KPCB_RAT

NCBI Description

plays a role in hexosamine biosynthesis pathway induced transcriptional regulation [RGD, Feb 2006]

Uniprot Description

PKCB: an AGC kinase of the PKC family. A classical PKC downstream of many mitogenic receptors. Activates the NF-kappaB signaling pathway in B cells after antigen-receptor signaling. Two splice-variant isoforms have been described.

Protein type: EC 2.7.11.13; Motility/polarity/chemotaxis; Kinase, protein; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); AGC group; PKC family; Alpha subfamily

Cellular Component: centrosome; membrane; brush border membrane; cytoplasm; plasma membrane; cytosol; nucleus

Molecular Function: protein serine/threonine kinase activity; protein binding; protein kinase C activity; protein kinase C binding; androgen receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; zinc ion binding; histone binding; calcium channel regulator activity; chromatin binding; ATP binding

Biological Process: response to drug; positive regulation of I-kappaB kinase/NF-kappaB cascade; transcription, DNA-dependent; B cell activation; dibenzo-p-dioxin metabolic process; apoptosis; positive regulation of B cell receptor signaling pathway; positive regulation of odontogenesis of dentine-containing teeth; negative regulation of insulin receptor signaling pathway; regulation of dopamine secretion; protein amino acid phosphorylation; positive regulation of vascular endothelial growth factor receptor signaling pathway; activation of NF-kappaB transcription factor; cellular calcium ion homeostasis; regulation of transcription from RNA polymerase II promoter; positive regulation of angiogenesis; B cell receptor signaling pathway; response to vitamin D; response to ethanol; regulation of growth; calcium ion transport; response to glucose stimulus; response to hypoxia

Research Articles on Prkcb

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Product Notes

The Prkcb prkcb (Catalog #AAA615518) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Protein Kinase C beta1 (PKCb1) reacts with Human, Mammal, Mouse, Rat, Rodent and may cross-react with other species as described in the data sheet. AAA Biotech's Protein Kinase C beta1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot (ECL): 1:1000. Decrease dilution of antibody if less senstive detecting system such as alkaline phosphatase is to be used. Optimal dilutions to be determined by researcher. Researchers should empirically determine the suitability of the Prkcb prkcb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Protein Kinase C beta1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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