Rabbit anti-Human PROSC Polyclonal Antibody | anti-PROSC antibody

PROSC, CT (PROSC, Proline synthase co-transcribed bacterial homolog protein) (APC)

Cat. Num. AAA6337579

• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: PROSC; Polyclonal Antibody; CT (PROSC; Proline synthase co-transcribed bacterial homolog protein) (APC); Proline synthase co-transcribed bacterial homolog protein; anti-PROSC antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-PROSC antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: PROSC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the C-terminal region of human PROSC.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(PROSC Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the PROSC antibody detected the PROSC protein (arrow).)

Related Product Information for anti-PROSC antibody

PROSC is ubiquitously expressed in human tissues and has been highly conserved among divergent species from bacteria to mammals, suggesting it has an important cellular function. PROSC is likely to be a soluble cytoplasmic protein, but its function remains to be determined. The P. aeruginosa homolog of this novel gene is located upstream of and may be cotranscribed with a known proline biosynthetic gene, hence the human gene was celled PROSC, for 'proline synthetase cotranscribed, bacterial homolog.'

Product Categories/Family for anti-PROSC antibody

Antibodies; Enzymes; Synthase

References

Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000). Ikegawa, S., et al. J. Hum. Genet. 44(5):337-342(1999).

NCBI and Uniprot Product Information

• NCBI GI #: 6005842
• NCBI GeneID: 11212
• NCBI Accession #: NP_009129.1
• NCBI GenBank Nucleotide #: NM_007198.3
• UniProt Accession #: O94903; Q6FI94
• Molecular Weight: 30,344 Da
• NCBI Official Full Name: proline synthase co-transcribed bacterial homolog protein
• NCBI Official Synonym Full Names: proline synthetase co-transcribed homolog (bacterial)
• NCBI Official Symbol: PROSC
• NCBI Protein Information: proline synthase co-transcribed bacterial homolog protein; proline synthetase co-transcribed (bacterial homolog); proline synthetase co-transcribed bacterial homolog protein
• UniProt Protein Name: Pyridoxal phosphate homeostasis protein
• Protein Family: Proline synthase co-transcribed bacterial homolog protein
• UniProt Gene Name: PLPBP
• UniProt Synonym Gene Names: PLP homeostasis protein

Uniprot Description

Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.