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Western Blot (WB) (Western blot analysis of PRKD3 expression in HEK293 cells, The lane on the left is treated with the antigen-specific peptide.)

Rabbit PRKD3 Polyclonal Antibody | anti-PRKD3 antibody

PRKD3 Antibody

Gene Names
PRKD3; EPK2; PKD3; PRKCN; PKC-NU; nPKC-NU
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
PRKD3; Polyclonal Antibody; PRKD3 Antibody; EPK 2; EPK2; KPCD3_HUMAN; nPKC nu; nPKC-nu; nPKCnu; nu; PKCnu; PKD 3; PKD3; PRK D3; PRKCN; PRKD 3; Prkd3; Protein kinase C; Protein kinase C nu; Protein kinase C nu type; Protein kinase D3; Protein kinase EPK 2; Protein kinase EPK2; Serine threonine protein kinase; Serine/threonine protein kinase D3; Serine/threonine-protein kinase D3; anti-PRKD3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
PRKD3 antibody detects endogenous levels of total PRKD3
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
890
Applicable Applications for anti-PRKD3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide
Subcellular Location
Cytoplasm. Membrane. Translocation to the cell membrane is required for kinase activation.
Tissue Specificity
Ubiquitous.
Predicted Cross Reactivity
Bovine, Sheep, Rabbit, Dog
Similarity
Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%)
Conjugation
Unconjugated

Western Blot (WB)

(Western blot analysis of PRKD3 expression in HEK293 cells, The lane on the left is treated with the antigen-specific peptide.)

Western Blot (WB) (Western blot analysis of PRKD3 expression in HEK293 cells, The lane on the left is treated with the antigen-specific peptide.)
Related Product Information for anti-PRKD3 antibody
Function: Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity).
Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 107 kDa
Predicted: 101 kDa
NCBI Official Full Name
serine/threonine-protein kinase D3
NCBI Official Synonym Full Names
protein kinase D3
NCBI Official Symbol
PRKD3
NCBI Official Synonym Symbols
EPK2; PKD3; PRKCN; PKC-NU; nPKC-NU
NCBI Protein Information
serine/threonine-protein kinase D3
UniProt Protein Name
Serine/threonine-protein kinase D3
UniProt Gene Name
PRKD3
UniProt Synonym Gene Names
EPK2; PRKCN

NCBI Description

This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain. The C-terminal region contains the catalytic domain and is distantly related to calcium-regulated kinases. Catalytic activity of this enzyme promotes its nuclear localization. This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation, growth regulation of breast and prostate cancer cells, and vesicle trafficking. [provided by RefSeq, Jan 2015]

Uniprot Description

Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress ().

Research Articles on PRKD3

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Product Notes

The PRKD3 prkd3 (Catalog #AAA9604188) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PRKD3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PRKD3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the PRKD3 prkd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRKD3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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