Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Mouse Preprovasopressin (VP) Polyclonal Antibody | anti-VP antibody
Polyclonal Antibody to Preprovasopressin (VP)
MGHHHHHHSGSEF- CYFQNCP RGGKRAISDM ELRQCLPCGP GGKGRCFGPS ICCADELGCF VGTAEALRCQ EENYLPSPCQ SGQKPCGSGG RCAAVGICCS DESCVAEPEC HDGFFRLTRA REPSNATQLD GPARALLLRL VQLAGTRESV DSAKPRVY
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:MouseTissue))
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:MouseTissue))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the vasopressin/oxytocin family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the neuropeptide hormone arginine vasopressin, and two other peptides, neurophysin 2 and copeptin. Arginine vasopressin binds to vasopressin receptors and functions as a vasopressor, to constrict blood vessels and increase blood pressure, and as an antidiuretic, to reduce the production of urine. Neurophysin 2 functions as a carrier protein in the transport of arginine vasopressin. This gene is present in a gene cluster with the related gene oxytocin on chromosome 2. [provided by RefSeq, Aug 2015]
Uniprot Description
AVP: Neurophysin 2 specifically binds vasopressin. Defects in AVP are the cause of diabetes insipidus, neurohypophyseal (NDI). A disease characterized by persistent thirst, polydipsia and polyuria. Affected individuals are apparently normal at birth, but characteristically develop symptoms of vasopression deficiency during childhood. Belongs to the vasopressin/oxytocin family.
Protein type: Hormone; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 2 F1|2 63.24 cM
Cellular Component: dendrite; extracellular region; extracellular space; secretory granule
Molecular Function: caspase inhibitor activity; hormone activity; neurohypophyseal hormone activity; neuropeptide hormone activity; protein kinase activity; signal transducer activity; V1A vasopressin receptor binding; V1B vasopressin receptor binding
Biological Process: elevation of cytosolic calcium ion concentration; grooming behavior; locomotory behavior; maternal behavior; multicellular organismal water homeostasis; negative regulation of apoptosis; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of female receptivity; negative regulation of transmission of nerve impulse; penile erection; positive regulation of cAMP biosynthetic process; positive regulation of cell growth; positive regulation of cell proliferation; positive regulation of cellular pH reduction; positive regulation of glutamate secretion; positive regulation of peptidyl-serine phosphorylation; positive regulation of prostaglandin biosynthetic process; positive regulation of systemic arterial blood pressure; positive regulation of vasoconstriction; regulation of blood vessel size; signal transduction; social behavior; vasoconstriction
Disease: Diabetes Insipidus, Neurohypophyseal
Research Articles on VP
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Product Notes
The VP avp (Catalog #AAA2004670) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Preprovasopressin (VP) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Preprovasopressin (VP) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the VP avp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF- CYFQNCP RGGKRAISDM ELRQCLPCGP GGKGRCFGPS ICCADELGCF VGTAEALRCQ EENYLPSPCQ SGQKPCGSGG RCAAVGICCS DESCVAEPEC HDGFFRLTRA REPSNATQLD GPARALLLRL VQLAGTRESV DSAKPRVY. It is sometimes possible for the material contained within the vial of "Preprovasopressin (VP), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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