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Rabbit anti-Mouse, Human PQLC2 Polyclonal Antibody | anti-PQLC2 antibody

PQLC2, CT (PQLC2, PQ-loop repeat-containing protein 2) (MaxLight 650)

Gene Names
SLC66A1; LAAT1; PQLC2; LAAT-1
Reactivity
Mouse, Human
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography
Synonyms
PQLC2; Polyclonal Antibody; CT (PQLC2; PQ-loop repeat-containing protein 2) (MaxLight 650); PQ-loop repeat-containing protein 2; anti-PQLC2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes mouse PQLC2. Species Crossreactivity: human
Purity/Purification
Purified by Protein A Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Sequence Length
291
Applicable Applications for anti-PQLC2 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P: 1:10-1:50
WB: 1:1000
Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids aa221-251 in the C-terminal region of human PQLC2. UniProt Accession #NP_060235.2; NP_001035214.1 Cellular Localization: Lysosome membrane; multi-pass membrane protein
Conjugate
MaxLight650
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Product Categories/Family for anti-PQLC2 antibody
References
1. Gregory, S.G., et al. Nature 441(7091):315-321(2006).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
lysosomal amino acid transporter 1 homolog isoform 1
NCBI Official Synonym Full Names
solute carrier family 66 member 1
NCBI Official Symbol
SLC66A1
NCBI Official Synonym Symbols
LAAT1; PQLC2; LAAT-1
NCBI Protein Information
lysosomal amino acid transporter 1 homolog
UniProt Protein Name
Lysosomal amino acid transporter 1 homolog
UniProt Gene Name
PQLC2

Uniprot Description

PQLC2: Lysosomal lysine/arginine transporter that specifically mediates the export of lysine and arginine from lysosomes. Belongs to the laat-1 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p36.13

Cellular Component: intracellular membrane-bound organelle; lysosomal membrane

Molecular Function: arginine transmembrane transporter activity; basic amino acid transmembrane transporter activity; L-lysine transmembrane transporter activity

Biological Process: arginine transport; lysine transport; transmembrane transport

Research Articles on PQLC2

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Product Notes

The PQLC2 pqlc2 (Catalog #AAA6336849) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PQLC2, CT (PQLC2, PQ-loop repeat-containing protein 2) (MaxLight 650) reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's PQLC2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 1:10-1:50 WB: 1:1000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PQLC2 pqlc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PQLC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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