Western Blot (WB)
(PPYR1 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PPYR1 antibody detected the PPYR1 protein (arrow).)
Rabbit anti-Human PPYR1 Polyclonal Antibody | anti-PPYR1 antibody
PPYR1, NT (PPYR1, NPY4R, Neuropeptide Y receptor type 4, Pancreatic polypeptide receptor 1) (Biotin)
Gene Names
NPY4R; Y4; PP1; PPYR1; NPY4-R
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PPYR1; Polyclonal Antibody; NT (PPYR1; NPY4R; Neuropeptide Y receptor type 4; Pancreatic polypeptide receptor 1) (Biotin); Pancreatic polypeptide receptor 1; anti-PPYR1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-PPYR1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
PPYR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PPYR1.
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(PPYR1 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PPYR1 antibody detected the PPYR1 protein (arrow).)
Western Blot (WB)
(PPYR1 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PPYR1 antibody detected the PPYR1 protein (arrow).)
Related Product Information for anti-PPYR1 antibody
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13-36) > PP (31-36) > NPY free acid.
Product Categories/Family for anti-PPYR1 antibody
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Umeda, T., et al. Peptides 30(8):1441-1447(2009). Sha, B.Y., et al. J. Hum. Genet. 54(4):199-202(2009). Gao, Y., et al. Biochemistry 47(43):11367-11376(2008). Parker, E., et al. Eur. J. Pharmacol. 440 (2-3), 173-187 (2002).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,195 Da
NCBI Official Full Name
neuropeptide Y receptor type 4
NCBI Official Synonym Full Names
neuropeptide Y receptor Y4
NCBI Official Symbol
NPY4R
NCBI Official Synonym Symbols
Y4; PP1; PPYR1; NPY4-R
NCBI Protein Information
neuropeptide Y receptor type 4; pancreatic polypeptide receptor 1
UniProt Protein Name
Neuropeptide Y receptor type 4
UniProt Gene Name
NPY4R
UniProt Synonym Gene Names
PPYR1; NPY4-R; PP1
UniProt Entry Name
NPY4R_HUMAN
Uniprot Description
NPY4R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13- 36) > PP (31-36) > NPY free acid. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral
Chromosomal Location of Human Ortholog: 10q11.2
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; peptide YY receptor activity; pancreatic polypeptide receptor activity; peptide binding
Biological Process: G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway; blood circulation; digestion; feeding behavior
Research Articles on PPYR1
Similar Products
Product Notes
The PPYR1 npy4r (Catalog #AAA6336821) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPYR1, NT (PPYR1, NPY4R, Neuropeptide Y receptor type 4, Pancreatic polypeptide receptor 1) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PPYR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PPYR1 npy4r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPYR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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