Western Blot (WB)
(Western Blot analysis of extracts of various cells, using PPP3R1 antibody.)
Rabbit PPP3R1 Polyclonal Antibody | anti-PPP3R1 antibody
PPP3R1 Polyclonal Antibody
Gene Names
PPP3R1; CNB; CNB1; CALNB1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
PPP3R1; Polyclonal Antibody; PPP3R1 Polyclonal Antibody; ALNB1; CNB; CNB1; anti-PPP3R1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
PPP3R1 polyclonal antibody detects endogenous levels of PPP3R1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
170
Applicable Applications for anti-PPP3R1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:100
IHC: 1:50-1:100
Immunogen
Recombinant protein of human PPP3R1.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using PPP3R1 antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using PPP3R1 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human prostate using PPP3R1 antibody at dilution of 1:100 (x40 lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human prostate using PPP3R1 antibody at dilution of 1:100 (x40 lens).)
Related Product Information for anti-PPP3R1 antibody
Protein phosphatase 3 (PPP3, formerly PP2B, Calcineurin), a serine/ threonine protein phosphatase, is a heterodimer composed of one catalytic subunit (PPP3C, Calcineurin A) and one regulatory subunit (PPP3R, Calcineurin B). PPP3R has two isoforms, PPP3R1 and PPP3R2. PPP3Rl is ubiquitously expressed in different tissues and is coded by the PPP3R1 gene which was mapped recently to human chromosome 2. PPP3Rl has four functional calcium-binding sites.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
~ 15kDa
NCBI Official Full Name
Calcineurin subunit B type 1
NCBI Official Synonym Full Names
protein phosphatase 3 regulatory subunit B, alpha
NCBI Official Symbol
PPP3R1
NCBI Official Synonym Symbols
CNB; CNB1; CALNB1
NCBI Protein Information
calcineurin subunit B type 1
UniProt Protein Name
Calcineurin subunit B type 1
UniProt Gene Name
PPP3R1
UniProt Synonym Gene Names
CNA2; CNB
UniProt Entry Name
CANB1_HUMAN
Uniprot Description
PPP3R1: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. Belongs to the calcineurin regulatory subunit family.
Protein type: Protein phosphatase, regulatory subunit; Cell development/differentiation; Apoptosis; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2p15
Cellular Component: nucleoplasm; cytosol; calcineurin complex; sarcolemma
Molecular Function: calmodulin binding; protein domain specific binding; protein binding; calcium-dependent protein serine/threonine phosphatase activity; calcium ion binding
Biological Process: calcineurin-NFAT signaling pathway; positive regulation of NFAT protein import into nucleus; dephosphorylation; apoptosis; innate immune response; positive regulation of transcription from RNA polymerase II promoter
Research Articles on PPP3R1
Similar Products
Product Notes
The PPP3R1 ppp3r1 (Catalog #AAA3008454) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPP3R1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PPP3R1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:100. Researchers should empirically determine the suitability of the PPP3R1 ppp3r1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPP3R1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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