Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Western blotAll lanes: PPP2R3C antibody at 3.76 ug/mlLane 1: Mouse stomach tissueLane 2: Mouse brain tissueLane 3: A431 whole cell lysateLane 4: Jurkat whole cell lysateLane 5: A549 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 54,40 kDaObserved band size: 53,30 kDa)

Rabbit anti-Human, Mouse PPP2R3C Polyclonal Antibody | anti-PPP2R3C antibody

PPP2R3C Antibody

Gene Names
PPP2R3C; G4-1; G5pr; C14orf10
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
PPP2R3C; Polyclonal Antibody; PPP2R3C Antibody; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma; Protein phosphatase subunit G5PR; Rhabdomyosarcoma antigen MU-RMS-40.6A/6C; C14orf10; G5PR; anti-PPP2R3C antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
343
Applicable Applications for anti-PPP2R3C antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma protein (N-160AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: PPP2R3C antibody at 3.76 ug/mlLane 1: Mouse stomach tissueLane 2: Mouse brain tissueLane 3: A431 whole cell lysateLane 4: Jurkat whole cell lysateLane 5: A549 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 54,40 kDaObserved band size: 53,30 kDa)

Western Blot (WB) (Western blotAll lanes: PPP2R3C antibody at 3.76 ug/mlLane 1: Mouse stomach tissueLane 2: Mouse brain tissueLane 3: A431 whole cell lysateLane 4: Jurkat whole cell lysateLane 5: A549 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 54,40 kDaObserved band size: 53,30 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain tissue using MBS7043685 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human brain tissue using MBS7043685 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7043685 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7043685 at dilution of 1:100)
Related Product Information for anti-PPP2R3C antibody
May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,806 Da
NCBI Official Full Name
serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform 2
NCBI Official Synonym Full Names
protein phosphatase 2 regulatory subunit B''gamma
NCBI Official Symbol
PPP2R3C
NCBI Official Synonym Symbols
G4-1; G5pr; C14orf10
NCBI Protein Information
serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma
UniProt Protein Name
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma
UniProt Gene Name
PPP2R3C
UniProt Synonym Gene Names
C14orf10; G5PR
UniProt Entry Name
P2R3C_HUMAN

NCBI Description

This gene encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

Uniprot Description

PPP2R3C: May regulate MCM3AP phosphorylation through phosphatase recruitment. May play a role in the activation-induced cell death of B-cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein phosphatase, regulatory subunit

Chromosomal Location of Human Ortholog: 14q13.2

Cellular Component: centrosome; spindle

Molecular Function: protein binding

Biological Process: B cell homeostasis; cortical cytoskeleton organization and biogenesis; microtubule cytoskeleton organization and biogenesis; positive regulation of B cell differentiation; T cell homeostasis

Research Articles on PPP2R3C

Similar Products

Product Notes

The PPP2R3C ppp2r3c (Catalog #AAA7043685) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPP2R3C Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PPP2R3C can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the PPP2R3C ppp2r3c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPP2R3C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.