Rabbit anti-Human PPP2R2D Polyclonal Antibody | anti-PPP2R2D antibody
PPP2R2D Antibody
IHC: 1:20-1:200
IF: 1:50-1:200
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Western Blot (WB)
(Positive WB detected in: U87 whole cell lysate, PC-3 whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysateAll lanes: PPP2R2D antibody at 3.3 μg/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 53 kDaObserved band size: 53 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7043885 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human glioma cancer using MBS7043885 at dilution of 1:100)
Immunofluorescence (IF)
(Immunofluorescent analysis of HeLa cells using MBS7043885 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
NCBI and Uniprot Product Information
Uniprot Description
PPP2R2D: B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55- delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment. Belongs to the phosphatase 2A regulatory subunit B family.
Protein type: Protein phosphatase, regulatory subunit
Chromosomal Location of Human Ortholog: 10q26.3
Cellular Component: protein phosphatase type 2A complex
Molecular Function: protein phosphatase type 2A regulator activity
Biological Process: exit from mitosis; mitosis
Research Articles on PPP2R2D
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Product Notes
The PPP2R2D ppp2r2d (Catalog #AAA7043885) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPP2R2D Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PPP2R2D can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:1000-1:5000 IHC: 1:20-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the PPP2R2D ppp2r2d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPP2R2D, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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