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Rabbit Porphyromonas gingivalis Gingipain R1 Polyclonal Antibody | anti-rgpA antibody

Rabbit anti-Porphyromonas gingivalis Gingipain R1 polyclonal Antibody

Reactivity
Porphyromonas gingivalis
Applications
ELISA
Purity
>95%, Protein G purified
Synonyms
Porphyromonas gingivalis Gingipain R1; Polyclonal Antibody; Rabbit anti-Porphyromonas gingivalis Gingipain R1 polyclonal Antibody; Gingipain R1 (EC 3.4.22.37) (Arg-gingipain) (Gingipain 1) (RGP-1); rgpA; rgp1; anti-rgpA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Porphyromonas gingivalis
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Applicable Applications for anti-rgpA antibody
ELISA (EIA)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant Porphyromonas gingivalis Gingipain R1 protein (228-720AA)
Species
Porphyromonas gingivalis
Research Area
Others
Target Names
rgpA
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Related Product Information for anti-rgpA antibody
Relevance:
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Its proteolytic activity is a major factor in both periodontal tissue destruction and in bacterial host defense mechanisms. Activates complement C3 and C5.

Description:
rgpA polyclonal antibody MBS1497288 was produced in the rabbit immunized by using the Recombinant Porphyromonas gingivalis Gingipain R1 protein (228-720AA) as the immunogen. The target protein rgpA is a thiol protease. It acts synergistically with RgpB to catalyze the maturation of fimbrial subunits, such as FimA (By similarity). Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms (Probable). it requires cysteine for activation and Ca2+ and/or Mg2+ for stabilization.
This Rabbit anti-Porphyromonas gingivalis rgpA Polyclonal antibody was tested in the ELISA. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It only reacts with the rgpA proteins of porphyromonas gingivalis-origin and may be used to detect the endogenous levels of rgpA protein.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
NCBI Official Full Name
Gingipain R1
UniProt Protein Name
Gingipain R1
Protein Family
UniProt Gene Name
rgpA
UniProt Synonym Gene Names
rgp1
UniProt Entry Name
CPG1_PORGN

Uniprot Description

Thiol protease. Acts synergistically with RgpB to catalyze the maturation of fimbrial subunits, such as FimA (). Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms (Probable).

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Product Notes

The Porphyromonas gingivalis Gingipain R1 rgpa (Catalog #AAA1497288) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Porphyromonas gingivalis Gingipain R1 polyclonal Antibody reacts with Porphyromonas gingivalis and may cross-react with other species as described in the data sheet. AAA Biotech's Porphyromonas gingivalis Gingipain R1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the Porphyromonas gingivalis Gingipain R1 rgpa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Porphyromonas gingivalis Gingipain R1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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