Western Blot (WB)
(Western Blot analysis of extracts of various cells, using POLE4 antibody.)
Rabbit anti-Human POLE4 Polyclonal Antibody | anti-POLE4 antibody
POLE4 Polyclonal Antibody
Gene Names
POLE4; p12; YHHQ1
Reactivity
Human
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
POLE4; Polyclonal Antibody; POLE4 Polyclonal Antibody; DNA polymerase epsilon subunit 4; DNA polymerase II subunit 4; DNA polymerase epsilon subunit p12; anti-POLE4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
POLE4 polyclonal antibody detects endogenous levels of POLE4 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
117
Applicable Applications for anti-POLE4 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant protein of human POLE4.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using POLE4 antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using POLE4 antibody.)
Related Product Information for anti-POLE4 antibody
DNA polymerase epsilon subunit 4, may play a role in allowing polymerase epsilon to carry out its replication and/or repair function.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 17kDa
NCBI Official Full Name
DNA polymerase epsilon subunit 4
NCBI Official Synonym Full Names
DNA polymerase epsilon 4, accessory subunit
NCBI Official Symbol
POLE4
NCBI Official Synonym Symbols
p12; YHHQ1
NCBI Protein Information
DNA polymerase epsilon subunit 4
UniProt Protein Name
DNA polymerase epsilon subunit 4
Protein Family
UniProt Gene Name
POLE4
UniProt Entry Name
DPOE4_HUMAN
NCBI Description
POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004]
Uniprot Description
POLE4: May play a role in allowing polymerase epsilon to carry out its replication and/or repair function.
Protein type: Nucleotide Metabolism - pyrimidine; EC 2.7.7.7; Transferase; Nucleotide Metabolism - purine
Chromosomal Location of Human Ortholog: 2p12
Cellular Component: epsilon DNA polymerase complex; nucleus
Molecular Function: protein binding; protein heterodimerization activity; sequence-specific DNA binding; DNA-directed DNA polymerase activity
Research Articles on POLE4
Similar Products
Product Notes
The POLE4 pole4 (Catalog #AAA3009335) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The POLE4 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's POLE4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the POLE4 pole4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "POLE4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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