Western Blot (WB)
(Host: RabbitTarget Name: POLA2Sample Type: Jurkat Whole Cell lysatesAntibody Dilution: 1.0ug/mlPOLA2 is supported by BioGPS gene expression data to be expressed in Jurkat)
Rabbit POLA2 Polyclonal Antibody | anti-POLA2 antibody
POLA2 Antibody - N-terminal region
Western Blot (WB)
(Host: RabbitTarget Name: POLA2Sample Type: Jurkat Whole Cell lysatesAntibody Dilution: 1.0ug/mlPOLA2 is supported by BioGPS gene expression data to be expressed in Jurkat)
Western Blot (WB)
(Host: RabbitTarget Name: POLA2Sample Type: Jurkat Whole Cell lysatesAntibody Dilution: 1.0ug/mlPOLA2 is supported by BioGPS gene expression data to be expressed in Jurkat)
Target Description: POLA2 may play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery.
NCBI and Uniprot Product Information
Uniprot Description
POLA2: a DNA polymerase that may play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery. DNA polymerase alpha-primase is a four subunit enzyme (subunits A, B, C and D), which is assembled throughout the cell cycle. The largest subunit (subunit A) has DNA polymerase activity, the two smallest subunits (subunits C and D) have DNA primase activity. Subunit B binds to subunit A. Phosphorylated in a cell cycle-dependent manner, in G2/M phase.
Protein type: Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; DNA replication
Chromosomal Location of Human Ortholog: 11q13.1
Cellular Component: nucleoplasm; alpha DNA polymerase:primase complex; cytoplasm
Molecular Function: DNA binding; protein heterodimerization activity; DNA-directed DNA polymerase activity
Biological Process: telomere maintenance via semi-conservative replication; DNA replication initiation; protein import into nucleus, translocation; telomere maintenance via recombination; mitotic cell cycle; DNA strand elongation during DNA replication; DNA replication; telomere maintenance; G1/S transition of mitotic cell cycle
Research Articles on POLA2
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Product Notes
The POLA2 pola2 (Catalog #AAA3217399) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The POLA2 Antibody - N-terminal region reacts with Horse, Human, Mouse, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's POLA2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the POLA2 pola2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: VGLTSEILNS FEHEFLSKRL SKARHSTCKD SGHAGARDIV SIQELIEVEE. It is sometimes possible for the material contained within the vial of "POLA2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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