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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7001717 at dilution of 1:100)

Rabbit anti-Human POGZ Polyclonal Antibody | anti-POGZ antibody

POGZ Antibody

Gene Names
POGZ; MRD37; WHSUS; ZNF635; ZNF280E; ZNF635m
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>95%,Protein G purified
Synonyms
POGZ; Polyclonal Antibody; POGZ Antibody; Pogo transposable element with ZNF domain; Suppressor of hairy wing homolog 5; Zinc finger protein 280E; Zinc finger protein 635; KIAA0461; SUHW5; ZNF280E; ZNF635; Nbla00003; anti-POGZ antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Sequence Length
1401
Applicable Applications for anti-POGZ antibody
ELISA (EIA), Immunohistochemistry (IHC)
Immunogen
Recombinant human Pogo transposable element with ZNF domain protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-102062
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7001717 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7001717 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7001717 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7001717 at dilution of 1:100)
Related Product Information for anti-POGZ antibody
Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
149,278 Da
NCBI Official Full Name
pogo transposable element with ZNF domain isoform 4
NCBI Official Synonym Full Names
pogo transposable element with ZNF domain
NCBI Official Symbol
POGZ
NCBI Official Synonym Symbols
MRD37; WHSUS; ZNF635; ZNF280E; ZNF635m
NCBI Protein Information
pogo transposable element with ZNF domain
UniProt Protein Name
Pogo transposable element with ZNF domain
UniProt Gene Name
POGZ
UniProt Synonym Gene Names
KIAA0461; SUHW5; ZNF280E; ZNF635
UniProt Entry Name
POGZ_HUMAN

NCBI Description

The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Aug 2010]

Uniprot Description

POGZ: a transposable element with a zinc-finger (ZNF) domain. Interacts with the Sp1 transcription factor (SP1). Four alternatively spliced isoforms have been described.

Protein type: C2H2-type zinc finger protein; Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: cytoplasm; nuclear chromatin; nucleoplasm; nucleus

Molecular Function: DNA binding; metal ion binding; protein binding

Biological Process: cell division; kinetochore assembly; mitotic sister chromatid cohesion

Disease: Mental Retardation, Autosomal Dominant 37

Research Articles on POGZ

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Product Notes

The POGZ pogz (Catalog #AAA7001717) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The POGZ Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's POGZ can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the POGZ pogz for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "POGZ, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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