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Western Blot (WB) (Western blot analysis of PODN using K562 whole cell lysates)

Rabbit anti-Human PODN Polyclonal Antibody | anti-PODN antibody

PODN Antibody

Gene Names
PODN; PCAN; SLRR5A
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
PODN; Polyclonal Antibody; PODN Antibody; 9430070G18; LRRGT00160; MGC24995; PCAN; Podn; PODN_HUMAN; Podocan; Podocan proteoglycan; RP23 40G2.7; SLRR5A; anti-PODN antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
PODN antibody detects endogenous levels of total PODN
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
642
Applicable Applications for anti-PODN antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human PODN
Subcellular Location
Cytoplasm and Secreted > Extracellular Space > Extracellular Matrix.
Tissue Specificity
Kidney, heart, liver, pancreas and vascular smooth muscle cells. Also detected in aortic intima (at protein level).
Predicted Cross Reactivity
Bovine, Horse, Sheep, Rabbit, Dog
Similarity
Bovine (100%), Horse (100%), Sheep (100%), Rabbit (92%), Dog (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of PODN using K562 whole cell lysates)

Western Blot (WB) (Western blot analysis of PODN using K562 whole cell lysates)
Related Product Information for anti-PODN antibody
Function: Negatively regulates cell proliferation and cell migration.
Subunit Structure: Binds to type I collagen.
Post-translational Modifications: N-glycosylated.
Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class V subfamily.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 69 kDa
Predicted: 69 kDa
NCBI Official Full Name
podocan isoform 2
NCBI Official Synonym Full Names
podocan
NCBI Official Symbol
PODN
NCBI Official Synonym Symbols
PCAN; SLRR5A
NCBI Protein Information
podocan
UniProt Protein Name
Podocan
Protein Family
UniProt Gene Name
PODN
UniProt Synonym Gene Names
SLRR5A

NCBI Description

The protein encoded by this gene is a member of the small leucine-rich repeat protein family and contains an amino terminal CX3CXCX7C cysteine-rich cluster followed by a leucine-rich repeat domain. Studies suggest that this protein could function to inhibit smooth muscle cell proliferation and migration following arterial injury. [provided by RefSeq, Jul 2016]

Uniprot Description

Negatively regulates cell proliferation and cell migration.

Research Articles on PODN

Similar Products

Product Notes

The PODN podn (Catalog #AAA9603026) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PODN Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PODN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the PODN podn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PODN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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