Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 47336(PNRC2 Antibody) at dilution 1/50.(Original magnification: 200))
Rabbit PNRC2 Polyclonal Antibody | anti-PNRC2 antibody
PNRC2 Antibody
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 47336(PNRC2 Antibody) at dilution 1/50.(Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 47336(PNRC2 Antibody) at dilution 1/50.(Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 47336(PNRC2 Antibody) at dilution 1/50.(Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 47336(PNRC2 Antibody) at dilution 1/50.(Original magnification: 200))
NCBI and Uniprot Product Information
Uniprot Description
Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery (PubMed:19150429). May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs (PubMed:19150429). Required for UPF1/RENT1 localization to the P-body (PubMed:19150429). Plays a role in glucocorticoid receptor-mediated mRNA degradation by interacting with the glucocorticoid receptor NR3C1 in a ligand-dependent manner when it is bound to the 5' UTR of target mRNAs and recruiting the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay (PubMed:25775514). Also acts as a nuclear receptor coactivator (PubMed:11574675). May play a role in controlling the energy balance between energy storage and energy expenditure ().
Research Articles on PNRC2
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Product Notes
The PNRC2 pnrc2 (Catalog #AAA9430319) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PNRC2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PNRC2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-300. Researchers should empirically determine the suitability of the PNRC2 pnrc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PNRC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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