Western Blot (WB)
(Western Blot analysis of extracts of various cells, using PMPCA antibody.)
Rabbit PMPCA Polyclonal Antibody | anti-PMPCA antibody
PMPCA Polyclonal Antibody
Gene Names
PMPCA; CLA1; CPD3; P-55; SCAR2; INPP5E; Alpha-MPP
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
PMPCA; Polyclonal Antibody; PMPCA Polyclonal Antibody; INPP5E; KIAA0123; MPPA; Alpha-MPP; P-55; alpha-MPP; MPP-alpha; MPPalpha; anti-PMPCA antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
PMPCA polyclonal antibody detects endogenous levels of PMPCA protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
394
Applicable Applications for anti-PMPCA antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant protein of human PMPCA.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using PMPCA antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using PMPCA antibody.)
Related Product Information for anti-PMPCA antibody
PMPCA (peptidase (mitochondrial processing) alpha), also known as alpha-MPP, P-55, INPP5E or MPPA, is a 525 amino acid protein that belongs to the peptidase M16 family and exists as a heterodimer of alpha and beta subunits. Localizing to mitochondrial matrix, PMPCA cleaves transit peptides from mitochondrial protein precursors. PMPCA is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 110kDa
NCBI Official Full Name
mitochondrial-processing peptidase subunit alpha isoform 2
NCBI Official Synonym Full Names
peptidase, mitochondrial processing subunit alpha
NCBI Official Symbol
PMPCA
NCBI Official Synonym Symbols
CLA1; CPD3; P-55; SCAR2; INPP5E; Alpha-MPP
NCBI Protein Information
mitochondrial-processing peptidase subunit alpha
UniProt Protein Name
Mitochondrial-processing peptidase subunit alpha
Protein Family
UniProt Gene Name
PMPCA
UniProt Synonym Gene Names
INPP5E; KIAA0123; MPPA
UniProt Entry Name
MPPA_HUMAN
NCBI Description
The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins. Defects in this gene are a cause of spinocerebellar ataxia, autosomal recessive 2. [provided by RefSeq, Mar 2016]
Research Articles on PMPCA
Similar Products
Product Notes
The PMPCA pmpca (Catalog #AAA3009361) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PMPCA Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PMPCA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the PMPCA pmpca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PMPCA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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