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Western Blot (WB) (Western blotAll lanes: PLSCR1 antibody at 2.24ug/mlLane 1:293T whole cell lysateLane 2:Hela whole cell lysateLane 3:HT29 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 36,27 kDaObserved band size: 35 kDa,85 kDa)

Rabbit anti-Human PLSCR1 Polyclonal Antibody | anti-PLSCR1 antibody

PLSCR1 Antibody

Gene Names
PLSCR1; MMTRA1B
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
PLSCR1; Polyclonal Antibody; PLSCR1 Antibody; Phospholipid scramblase 1; PL scramblase 1; Ca(2+)-dependent phospholipid scramblase 1; Erythrocyte phospholipid scramblase; MmTRA1b; anti-PLSCR1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
318
Applicable Applications for anti-PLSCR1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human Phospholipid scramblase 1 protein (1-318AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-27779
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: PLSCR1 antibody at 2.24ug/mlLane 1:293T whole cell lysateLane 2:Hela whole cell lysateLane 3:HT29 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 36,27 kDaObserved band size: 35 kDa,85 kDa)

Western Blot (WB) (Western blotAll lanes: PLSCR1 antibody at 2.24ug/mlLane 1:293T whole cell lysateLane 2:Hela whole cell lysateLane 3:HT29 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 36,27 kDaObserved band size: 35 kDa,85 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7045108 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7045108 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human spleen tissue using MBS7045108 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human spleen tissue using MBS7045108 at dilution 1:100)
Related Product Information for anti-PLSCR1 antibody
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,825 Da
NCBI Official Full Name
phospholipid scramblase 1
NCBI Official Synonym Full Names
phospholipid scramblase 1
NCBI Official Symbol
PLSCR1
NCBI Official Synonym Symbols
MMTRA1B
NCBI Protein Information
phospholipid scramblase 1
UniProt Protein Name
Phospholipid scramblase 1
Protein Family
UniProt Gene Name
PLSCR1
UniProt Synonym Gene Names
PL scramblase 1
UniProt Entry Name
PLS1_HUMAN

Uniprot Description

PLSCR1: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Belongs to the phospholipid scramblase family.

Protein type: Calcium-binding; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q23

Cellular Component: cytosol; extracellular matrix; Golgi apparatus; integral to plasma membrane; lipid raft; membrane; nucleolus; nucleus; plasma membrane

Molecular Function: calcium ion binding; CD4 receptor binding; enzyme binding; epidermal growth factor receptor binding; phospholipid scramblase activity; protein binding; SH3 domain binding

Biological Process: acute-phase response; apoptosis; defense response to virus; negative regulation of viral genome replication; phosphatidylserine biosynthetic process; phospholipid scrambling; positive regulation of innate immune response; positive regulation of transcription from RNA polymerase II promoter; regulation of mast cell activation

Research Articles on PLSCR1

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Product Notes

The PLSCR1 plscr1 (Catalog #AAA7045108) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLSCR1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PLSCR1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the PLSCR1 plscr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLSCR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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