Rabbit PLD6 Polyclonal Antibody | anti-PLD6 antibody

Rabbit anti-Danio rerio (Zebrafish)(Brachydanio rerio) PLD6 Polyclonal Antibody

• Gene Names: pld6; fc55d08; wu:fc55d08; zgc:162591
• Reactivity: Danio rerio (Zebrafish)(Brachydanio rerio)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: PLD6; Polyclonal Antibody; Rabbit anti-Danio rerio (Zebrafish)(Brachydanio rerio) PLD6 Polyclonal Antibody; PLD6 Antibody; Mitochondrial cardiolipin hydrolase; EC 3.1.-.-; Choline phosphatase 6; Mitochondrial phospholipase; MitoPLD; Phosphatidylcholine-hydrolyzing phospholipase D6; Phospholipase D6; PLD 6; pld6 zgc:162591; anti-PLD6 antibody

• Host: Rabbit
• Reactivity: Danio rerio (Zebrafish)(Brachydanio rerio)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-PLD6 antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) pld6 protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 148225260
• NCBI GeneID: 567338
• NCBI Accession #: NP_001082883.1
• NCBI GenBank Nucleotide #: NM_001089414.1
• UniProt Accession #: A3KNW0; B8A667
• Molecular Weight: 25,866 Da
• NCBI Official Full Name: mitochondrial cardiolipin hydrolase
• NCBI Official Synonym Full Names: phospholipase D family, member 6
• NCBI Official Symbol: pld6
• NCBI Official Synonym Symbols: fc55d08; wu:fc55d08; zgc:162591
• NCBI Protein Information: mitochondrial cardiolipin hydrolase; PLD 6; mitoPLD; phospholipase D6; choline phosphatase 6; mitochondrial phospholipase; phosphatidylcholine-hydrolyzing phospholipase D6; probable phospholipase D family member FLJ33580 homolog
• UniProt Protein Name: Mitochondrial cardiolipin hydrolase
• Protein Family: Mitochondrial cardiolipin hydrolase
• UniProt Gene Name: pld6
• UniProt Synonym Gene Names: MitoPLD; PLD 6
• UniProt Entry Name: PLD6_DANRE

Uniprot Description

Regulates mitochondrial shape through facilitating mitochondrial fusion. During spermatogenesis, plays a critical role in PIWI-interacting RNA (piRNA) biogenesis (). piRNAs provide essential protection against the activity of mobile genetic elements. piRNA-mediated transposon silencing is thus critical for maintaining genome stability, in particular in germline cells when transposons are mobilized as a consequence of wide-spread genomic demethylation. Has been shown to be a backbone-non-specific, single strand-specific nuclease, cleaving either RNA or DNA substrates with similar affinity (). Produces 5' phosphate and 3' hydroxyl termini, suggesting it could directly participate in the processing of primary piRNA transcripts (). Has been proposed to act as a cardiolipin hydrolase to generate phosphatidic acid at mitochondrial surface. Although it cannot be excluded that it can act as a phospholipase in some circumstances, this activity could not be confirmed ().