Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PLCG2 antibody (Tyr1217))
Rabbit PLCG2 Polyclonal Antibody | anti-PLCG2 antibody
PLCG2 Antibody (Tyr1217)
Gene Names
PLCG2; FCAS3; APLAID; PLC-IV; PLC-gamma-2
Applications
Immunohistochemistry
Purity
Affinity Chromatography
Synonyms
PLCG2; Polyclonal Antibody; PLCG2 Antibody (Tyr1217); Rabbit Polyclonal PLCG2 Antibody (Tyr1217); Polyclonal PLCG2 antibody; Anti-PLCG2 antibody; 1-phosphatidylinositol-4 5-bisphosphate phosphodiesterase gamma-2 antibody; Phosphoinositide phospholipase C-gamma-2 antibody; phospholipase C gamma 2 antibody; phospholipase C gamma 2 (phosphatidylinositol-specific) antibody; phospholipase C gamma 2 (phosphatidylyinositol-specific) antibody; Phospholipase C-gamma-2 antibody; Phospholipase C-IV antibody; PLC-gamma-2 antibody; PLC-IV antibody; PLCG2 antibody; anti-PLCG2 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
PLCG2 antibody (Tyr1217) detects endogenous levels of PLCG2 onlywhenphosphorylated at tyrosine 1217
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
1265
Applicable Applications for anti-PLCG2 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-100
Immunogen
PLCG2 antibody was raised in Rabbit using a synthesized phosphopeptide derived from human PLCG2 around the phosphorylation site of tyrosine 1217 (F-L-YP-D-T) as the immunogen.
Cross-Reactivity
Mouse, Rat
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeat freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PLCG2 antibody (Tyr1217))
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PLCG2 antibody (Tyr1217))
Related Product Information for anti-PLCG2 antibody
PLCG2 is a crucial enzyme in transmembrane signaling.
Product Categories/Family for anti-PLCG2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
PLCG2 protein
NCBI Official Synonym Full Names
phospholipase C gamma 2
NCBI Official Symbol
PLCG2
NCBI Official Synonym Symbols
FCAS3; APLAID; PLC-IV; PLC-gamma-2
NCBI Protein Information
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
Protein Family
NCBI Description
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]
Research Articles on PLCG2
Similar Products
Product Notes
The PLCG2 (Catalog #AAA5313740) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PLCG2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-100. Researchers should empirically determine the suitability of the PLCG2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLCG2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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