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Testing Data

Rabbit PLCB2 Polyclonal Antibody | anti-PLCB2 antibody

PLCB2 Antibody

Gene Names
PLCB2; PLC-beta-2
Reactivity
Human
Predicted: Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
PLCB2; Polyclonal Antibody; PLCB2 Antibody; anti-PLCB2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Clonality
Polyclonal
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
Sequence Length
1658
Applicable Applications for anti-PLCB2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-1:80,000
WB: 1:1,000-1:2,000
IHC: 1:100-1:500
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

Testing Data

Testing Data

Testing Data

Testing Data
Related Product Information for anti-PLCB2 antibody
Rabbit polyclonal PLCB2 (1) antibody was raised against a recombinate human PLCB2 protein 1-198aa (BC000939).
References
(1) Cartier, A., Parent, A., Labrecque, P. et al. WDR36 acts as a scaffold protein tethering a G-protein-coupled receptor, Galphaq and phospholipase Cbeta in a signalling complex. J. Cell. Sci. 124 (PT 19), 3292-3304 (2011).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
132,511 Da
NCBI Official Full Name
Homo sapiens phospholipase C, beta 2, mRNA
NCBI Official Synonym Full Names
phospholipase C beta 2
NCBI Official Symbol
PLCB2
NCBI Official Synonym Symbols
PLC-beta-2
NCBI Protein Information
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
UniProt Protein Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
UniProt Gene Name
PLCB2
UniProt Synonym Gene Names
PLC-beta-2

NCBI Description

The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses. [provided by RefSeq, Jan 2017]

Uniprot Description

The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

Research Articles on PLCB2

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Product Notes

The PLCB2 plcb2 (Catalog #AAA8502809) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLCB2 Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PLCB2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-1:80,000 WB: 1:1,000-1:2,000 IHC: 1:100-1:500. Researchers should empirically determine the suitability of the PLCB2 plcb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLCB2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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