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Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human brain tissue, using IPKB antibody.)

Rabbit anti-Human, Mouse PKIB Polyclonal Antibody | anti-PKIB antibody

PKIB Antibody

Gene Names
PKIB; PRKACN2
Reactivity
Human, Mouse
Applications
ELISA, Immunohistochemistry, Immunofluorescence
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
PKIB; Polyclonal Antibody; PKIB Antibody; PKI-beta; cAMP-dependent protein kinase inhibitor beta; PRKACN2; anti-PKIB antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid; Rabbit IgG In Phosphate Buffered Saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
Applicable Applications for anti-PKIB antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IHC: 1:50-1:100
IF: 1:100-1:500
Immunogen
Synthesized peptide derived from internal of human IPKB.
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human brain tissue, using IPKB antibody.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human brain tissue, using IPKB antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of MCF-7 cells, using IPKB antibody.)

Immunofluorescence (IF) (Immunofluorescence analysis of MCF-7 cells, using IPKB antibody.)
Product Categories/Family for anti-PKIB antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
8,468 Da
NCBI Official Full Name
cAMP-dependent protein kinase inhibitor beta isoform 1
NCBI Official Synonym Full Names
protein kinase (cAMP-dependent, catalytic) inhibitor beta
NCBI Official Symbol
PKIB
NCBI Official Synonym Symbols
PRKACN2
NCBI Protein Information
cAMP-dependent protein kinase inhibitor beta; PKI-beta; cAMP-dependent protein kinase inhibitor 2
UniProt Protein Name
cAMP-dependent protein kinase inhibitor beta
UniProt Gene Name
PKIB
UniProt Synonym Gene Names
PRKACN2; PKI-beta
UniProt Entry Name
IPKB_HUMAN

NCBI Description

This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Uniprot Description

PKIB: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. Belongs to the PKI family.

Protein type: Protein kinase, regulatory subunit; Inhibitor

Chromosomal Location of Human Ortholog: 6q22.31

Cellular Component: cytoplasm; nucleus

Molecular Function: cAMP-dependent protein kinase inhibitor activity

Research Articles on PKIB

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Product Notes

The PKIB pkib (Catalog #AAA7132297) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PKIB Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PKIB can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). IHC: 1:50-1:100 IF: 1:100-1:500. Researchers should empirically determine the suitability of the PKIB pkib for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PKIB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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