Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded section of Human Mammary Cancer Tissue)
Rabbit PKC Alpha Polyclonal Antibody | anti-PKCA antibody
PKC Alpha Antibody
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded section of Human Mammary Cancer Tissue)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded section of Human Mammary Cancer Tissue)
Western Blot (WB)
(Western Blot using Hela Cell Lysate)
Western Blot (WB)
(Western Blot using Hela Cell Lysate)
NCBI and Uniprot Product Information
Uniprot Description
PKCA: an AGC kinase of the PKC family. A classical PKC downstream of many mitogenic and receptors. Classical PKCs are calcium-dependent enzymes that are activated by phosphatidylserine, diacylglycerol and phorbol esters. Contains a pseudo-substrate autoinhibitory domain that binds to the catalytic domain preventing its activation in the absence of cofactors or activators.
Protein type: EC 2.7.11.13; Kinase, protein; Protein kinase, AGC; Oncoprotein; Protein kinase, Ser/Thr (non-receptor); AGC group; PKC family; Alpha subfamily
Cellular Component: cytoplasm; cytosol; intracellular; mitochondrial membrane; nucleus; perinuclear region of cytoplasm; plasma membrane
Molecular Function: ATP binding; protein binding; protein kinase C activity; zinc ion binding
Biological Process: adenylate cyclase activation; angiogenesis; apoptosis; cell adhesion; negative regulation of adenylate cyclase activity; peptidyl-serine phosphorylation; positive regulation of angiogenesis; positive regulation of cell adhesion; positive regulation of cell migration; positive regulation of endothelial cell proliferation; positive regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of macrophage differentiation; positive regulation of mitotic cell cycle; protein amino acid phosphorylation
Research Articles on PKCA
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Product Notes
The PKCA prkca (Catalog #AAA5312573) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PKC Alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the PKCA prkca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PKC Alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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