Immunofluorescence (IF)
(Immunofluorescence analysis of U2OS cells using PJA2 Polyclonal Antibody )
Rabbit PJA2 Polyclonal Antibody | anti-PJA2 antibody
PJA2 Polyclonal Antibody
Immunofluorescence (IF)
(Immunofluorescence analysis of U2OS cells using PJA2 Polyclonal Antibody )
Immunofluorescence (IF)
(Immunofluorescence analysis of U2OS cells using PJA2 Polyclonal Antibody )
NCBI and Uniprot Product Information
Uniprot Description
PJA2: Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA- mediated long-term memory processes. Binds ubiquitin-conjugating enzymes (E2s). In vitro, interacts with the ubiquitin-conjugating enzyme, UBE2D2. The phosphorylated form interacts with PRKAR1A, PRKAR2A and PRKAR2B. Binds the catalytic subunits of cAMP-dependent protein kinase. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 6.3.2.-; EC 6.3.2.19; Ligase; Ubiquitin ligase; Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 5q21.3
Cellular Component: Golgi membrane; postsynaptic membrane; endoplasmic reticulum membrane; cytoplasm; postsynaptic density; plasma membrane; cell junction
Molecular Function: zinc ion binding; ubiquitin-protein ligase activity; ligase activity
Biological Process: long-term memory; protein ubiquitination
Research Articles on PJA2
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Product Notes
The PJA2 pja2 (Catalog #AAA2566587) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PJA2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PJA2 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF). IF: 1:50-1:100. Researchers should empirically determine the suitability of the PJA2 pja2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PJA2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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