Western Blot (WB)
(Western blot analysis of PINCH-2 expression in HeLa (A), rat liver (B) whole cell lysates.)
Rabbit anti-Human, Rat PINCH-2 Polyclonal Antibody | anti-PINCH-2 antibody
Anti-PINCH-2 Antibody
Western Blot (WB)
(Western blot analysis of PINCH-2 expression in HeLa (A), rat liver (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of PINCH-2 expression in HeLa (A), rat liver (B) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Uniprot Description
LIMS2: Competes with LIMS1 for binding to ILK. Plays a role in modulating cell spreading and migration. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 2q14.3
Cellular Component: focal adhesion; plasma membrane; nucleus; cytosol
Molecular Function: zinc ion binding
Biological Process: intercellular junction assembly and maintenance; cell-cell adhesion; negative regulation of apoptosis
Research Articles on PINCH-2
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Product Notes
The PINCH-2 lims2 (Catalog #AAA8307156) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PINCH-2 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PINCH-2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the PINCH-2 lims2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PINCH-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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