Testing Data
(Sample (30ug whole cell lysate)A: A4317.5% SDS PAGEPrimary antibody diluted at 1: 1000)
Rabbit anti-Human PIK3R3 Polyclonal Antibody | anti-PIK3R3 antibody
PIK3R3 antibody
Immunohistochemistry: 1:50-1:500
Testing Data
(Sample (30ug whole cell lysate)A: A4317.5% SDS PAGEPrimary antibody diluted at 1: 1000)
Testing Data
(Sample (30ug whole cell lysate)A: A4317.5% SDS PAGEPrimary antibody diluted at 1: 1000)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded SAS xenograft, using PIK3R3 antibody at 1: 500 dilution.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded SAS xenograft, using PIK3R3 antibody at 1: 500 dilution.)
NCBI and Uniprot Product Information
Uniprot Description
PIK3R3: Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. Heterodimer of a regulatory subunit PIK3R3 and a p110 catalytic subunit (PIK3CA, PIK3CB or PIK3CD). Interacts with AXL. Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle. Belongs to the PI3K p85 subunit family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Kinase, lipid
Chromosomal Location of Human Ortholog: 1p34.1
Cellular Component: cytosol; phosphoinositide 3-kinase complex
Molecular Function: protein binding; 1-phosphatidylinositol-3-kinase activity; phosphoinositide 3-kinase regulator activity
Biological Process: phospholipid metabolic process; phosphatidylinositol biosynthetic process; insulin receptor signaling pathway; regulation of phosphoinositide 3-kinase activity
Research Articles on PIK3R3
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Product Notes
The PIK3R3 pik3r3 (Catalog #AAA9400678) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PIK3R3 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PIK3R3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500-1:3000 Immunohistochemistry: 1:50-1:500. Researchers should empirically determine the suitability of the PIK3R3 pik3r3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIK3R3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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