Western Blot (WB)
(Western Blot (WB) analysis of PIGW polyclonal antibody at 1:500 dilution Lane1:293T whole cell lysate Lane2:NIH-3T3 whole cell lysate Lane3:H9C2 whole cell lysate)
Rabbit PIGW Polyclonal Antibody | anti-PIGW antibody
PIGW Polyclonal Antibody
Aliquot and store at -24 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of PIGW polyclonal antibody at 1:500 dilution Lane1:293T whole cell lysate Lane2:NIH-3T3 whole cell lysate Lane3:H9C2 whole cell lysate)
Western Blot (WB)
(Western Blot (WB) analysis of PIGW polyclonal antibody at 1:500 dilution Lane1:293T whole cell lysate Lane2:NIH-3T3 whole cell lysate Lane3:H9C2 whole cell lysate)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an inositol acyltransferase that acylates the inositol ring of phosphatidylinositol. This occurs in the endoplasmic reticulum and is a step in the biosynthesis of glycosylphosphatidylinositol (GPI), which anchors many cell surface proteins to the membrane. Defects in this gene are a cause of the age-dependent epileptic encephalopathy West syndrome as well as a syndrome exhibiting hyperphosphatasia and cognitive disability (HPMRS5). [provided by RefSeq, Jul 2017]
Uniprot Description
PIGW: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI- anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins. Belongs to the PIGW family.
Protein type: EC 2.3.-.-; Endoplasmic reticulum; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, integral; Membrane protein, multi-pass; Transferase
Chromosomal Location of Human Ortholog: 17q12
Cellular Component: endoplasmic reticulum membrane; integral component of membrane
Molecular Function: O-acyltransferase activity
Biological Process: GPI anchor metabolic process; preassembly of GPI anchor in ER membrane
Disease: Hyperphosphatasia With Mental Retardation Syndrome 5
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Product Notes
The PIGW pigw (Catalog #AAA3007318) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PIGW Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PIGW can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the PIGW pigw for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIGW, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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