Western Blot (WB)
(PIGP Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the PIGP antibody detected the PIGP protein (arrow).)
Rabbit anti-Human PIGP Polyclonal Antibody | anti-PIGP antibody
PIGP Antibody (N-term)
Western Blot (WB)
(PIGP Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the PIGP antibody detected the PIGP protein (arrow).)
Western Blot (WB)
(PIGP Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the PIGP antibody detected the PIGP protein (arrow).)
glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The
GPI-anchor is a glycolipid found on many blood cells that serves to
anchor proteins to the cell surface. The encoded protein is a
component of the GPI-N-acetylglucosaminyltransferase complex that
catalyzes the transfer of N-acetylglucosamine (GlcNAc) from
UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in
the Down Syndrome critical region on chromosome 21 and is a
candidate for the pathogenesis of Down syndrome. Alternatively
spliced transcript variants encoding different isoforms have been
described.
Ferrando-Miguel, R., et al. Amino Acids 26(3):255-261(2004)
Choi, D.K., et al. Mamm. Genome 12(5):347-351(2001)
Kinoshita, T., et al. Curr Opin Chem Biol 4(6):632-638(2000)
Watanabe, R., et al. EMBO J. 19(16):4402-4411(2000)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
PIGP: Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. Belongs to the PIGP family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Transferase; Membrane protein, integral; EC 2.4.1.198
Chromosomal Location of Human Ortholog: 21q22.2
Cellular Component: glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; endoplasmic reticulum membrane; integral to membrane
Molecular Function: phosphatidylinositol N-acetylglucosaminyltransferase activity
Biological Process: cellular protein metabolic process; preassembly of GPI anchor in ER membrane; C-terminal protein lipidation; post-translational protein modification
Research Articles on PIGP
Similar Products
Product Notes
The PIGP pigp (Catalog #AAA9204847) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-30. The PIGP Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PIGP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the PIGP pigp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIGP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
