Western Blot (WB)
(Western blot analysis of extracts from C6 cells, untreated or PMA-stimulated for the indicated times, using Phospho-PLD1 (Ser561) Antibody (upper) or PLD1 P4074-50 (lower).)
Rabbit Phospholipase D1 Polyclonal Antibody | anti-Pld1 antibody
Phospholipase D1, phosphorylated (PLD1) (Ser561)
Purified by protein A and peptide affinity chromatography.
Purified by protein A and peptide affinity chromatography.
Dilution: Western Blot: 1:1000
Western Blot (WB)
(Western blot analysis of extracts from C6 cells, untreated or PMA-stimulated for the indicated times, using Phospho-PLD1 (Ser561) Antibody (upper) or PLD1 P4074-50 (lower).)
Western Blot (WB)
(Western blot analysis of extracts from C6 cells, untreated or PMA-stimulated for the indicated times, using Phospho-PLD1 (Ser561) Antibody (upper) or PLD1 P4074-50 (lower).)
NCBI and Uniprot Product Information
NCBI Description
ubiquitous enzyme that hydrolyzes phosphatidylcholine to phosphatidic acid (PA) and choline [RGD]
Uniprot Description
PLD1: a phosphatidylcholine-hydrolyzing phospholipase. Activated by ADP-ribosylated Rho and protein kinase C. Implicated as a critical step in numerous cellular pathways including membrane trafficking and the regulation polymorphonuclear leukocyte degranulation and oxidant production. May be involved in the regulation of perinuclear intravesicular membrane traffic. Four splice-variant isoforms have been described.
Protein type: EC 3.1.4.4; Motility/polarity/chemotaxis; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - ether lipid; Phospholipase
Cellular Component: Golgi apparatus; Golgi cisterna; endoplasmic reticulum membrane; intracellular membrane-bound organelle; lysosomal membrane; late endosome membrane; Golgi membrane; membrane; perinuclear region of cytoplasm; endocytic vesicle; lamellipodium; apical plasma membrane; endosome; vesicle
Molecular Function: protein binding; phospholipase D activity; catalytic activity; phosphoinositide binding
Biological Process: response to peptide hormone stimulus; defense response to Gram-positive bacterium; metabolic process; phospholipid catabolic process; phosphatidic acid biosynthetic process; regulation of microvillus biogenesis; positive regulation of cell migration; phospholipid biosynthetic process
Research Articles on Pld1
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Product Notes
The Pld1 pld1 (Catalog #AAA613752) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Phospholipase D1, phosphorylated (PLD1) (Ser561) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Phospholipase D1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot: 1:1000. Researchers should empirically determine the suitability of the Pld1 pld1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Phospholipase D1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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