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Immunohistochemistry (IHC) (Immunohistochemistry with Human Tonsil lysate tissue at an antibody concentration of 5.0ug/ml using anti-PHACTR1 antibody )

Rabbit PHACTR1 Polyclonal Antibody | anti-PHACTR1 antibody

PHACTR1 antibody - middle region

Gene Names
PHACTR1; RPEL; RPEL1; EIEE70; dJ257A7.2
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Applications
Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
PHACTR1; Polyclonal Antibody; PHACTR1 antibody - middle region; anti-PHACTR1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: QRPTAEELEQRNILKPRNEQEEQEEKREIKRRLTRKLSQRPTVEELRERK
Sequence Length
580
Applicable Applications for anti-PHACTR1 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 90%; Zebrafish: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PHACTR1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry with Human Tonsil lysate tissue at an antibody concentration of 5.0ug/ml using anti-PHACTR1 antibody )

Immunohistochemistry (IHC) (Immunohistochemistry with Human Tonsil lysate tissue at an antibody concentration of 5.0ug/ml using anti-PHACTR1 antibody )

Western Blot (WB)

(WB Suggested Anti-PHACTR1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate)

Western Blot (WB) (WB Suggested Anti-PHACTR1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate)
Related Product Information for anti-PHACTR1 antibody
This is a rabbit polyclonal antibody against PHACTR1. It was validated on Western Blot using a cell lysate as a positive control.

Target Description: PHACTR1 belongs to the phosphatase and actin regulator family. It contains 4 RPEL repeats. The function of the PHACTR1 protein remains unknown.
Product Categories/Family for anti-PHACTR1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
66kDa
NCBI Official Full Name
phosphatase and actin regulator 1 isoform a
NCBI Official Synonym Full Names
phosphatase and actin regulator 1
NCBI Official Symbol
PHACTR1
NCBI Official Synonym Symbols
RPEL; RPEL1; EIEE70; dJ257A7.2
NCBI Protein Information
phosphatase and actin regulator 1
UniProt Protein Name
Phosphatase and actin regulator 1
UniProt Gene Name
PHACTR1
UniProt Synonym Gene Names
KIAA1733; RPEL1
UniProt Entry Name
PHAR1_HUMAN

NCBI Description

The protein encoded by this gene is a member of the phosphatase and actin regulator family of proteins. This family member can bind actin and regulate the reorganization of the actin cytoskeleton. It plays a role in tubule formation and in endothelial cell survival. Polymorphisms in this gene are associated with susceptibility to myocardial infarction, coronary artery disease and cervical artery dissection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]

Uniprot Description

PHACTR1: Belongs to the phosphatase and actin regulator family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 6p24.1

Cellular Component: synapse; cell junction; cytosol; nucleus

Molecular Function: protein phosphatase type 1 regulator activity; protein phosphatase inhibitor activity; actin binding; protein phosphatase 1 binding

Biological Process: actomyosin structure organization and biogenesis; negative regulation of catalytic activity; actin cytoskeleton reorganization; stress fiber formation; cell motility involved in cell locomotion

Research Articles on PHACTR1

Similar Products

Product Notes

The PHACTR1 phactr1 (Catalog #AAA3212196) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PHACTR1 antibody - middle region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's PHACTR1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the PHACTR1 phactr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: QRPTAEELEQ RNILKPRNEQ EEQEEKREIK RRLTRKLSQR PTVEELRERK. It is sometimes possible for the material contained within the vial of "PHACTR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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