Rabbit PHACTR1 Polyclonal Antibody | anti-PHACTR1 antibody
PHACTR1 antibody - middle region
Target Description: PHACTR1 belongs to the phosphatase and actin regulator family. It contains 4 RPEL repeats. The function of the PHACTR1 protein remains unknown.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the phosphatase and actin regulator family of proteins. This family member can bind actin and regulate the reorganization of the actin cytoskeleton. It plays a role in tubule formation and in endothelial cell survival. Polymorphisms in this gene are associated with susceptibility to myocardial infarction, coronary artery disease and cervical artery dissection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
Uniprot Description
PHACTR1: Belongs to the phosphatase and actin regulator family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 6p24.1
Cellular Component: synapse; cell junction; cytosol; nucleus
Molecular Function: protein phosphatase type 1 regulator activity; protein phosphatase inhibitor activity; actin binding; protein phosphatase 1 binding
Biological Process: actomyosin structure organization and biogenesis; negative regulation of catalytic activity; actin cytoskeleton reorganization; stress fiber formation; cell motility involved in cell locomotion
Research Articles on PHACTR1
Similar Products
Product Notes
The PHACTR1 phactr1 (Catalog #AAA3212196) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PHACTR1 antibody - middle region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's PHACTR1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the PHACTR1 phactr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: QRPTAEELEQ RNILKPRNEQ EEQEEKREIK RRLTRKLSQR PTVEELRERK. It is sometimes possible for the material contained within the vial of "PHACTR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.