Western Blot (WB)
((0.1ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat PGRMC1/MPR Polyclonal Antibody | anti-PGRMC1 antibody
Goat anti-PGRMC1/MPR Antibody
Gene Names
PGRMC1; MPR; HPR6.6
Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
PGRMC1/MPR; Polyclonal Antibody; Goat anti-PGRMC1/MPR Antibody; PGRMC1; MPR; progesterone receptor membrane component 1; HGNC: 16090; HPR6. 6; progesterone binding protein; PGRMC1 antibody; MPR antibody; progesterone receptor membrane component 1 antibody; HGNC: 16090 antibody; HPR6. 6 antibody; progesterone binding protein antibody; PGRMC1 / MPR; anti-PGRMC1 antibody
Host
Goat
Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
EPKDESARKND
Sequence Length
195
Applicable Applications for anti-PGRMC1 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 4000.
Immunogen
Peptide with sequence C-EPKDESARKND, from the C Terminus of the protein sequence according to NP_006658.1.
Epitope
C Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Western Blot (WB)
((0.1ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((0.1ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
(HEK293 overexpressing Human PGRMC1 (RC201918) and probed (mock transfection in first lane), tested by Origene. Result obtained with a previous batch.)
Western Blot (WB)
(HEK293 overexpressing Human PGRMC1 (RC201918) and probed (mock transfection in first lane), tested by Origene. Result obtained with a previous batch.)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
15,879 Da
NCBI Official Full Name
membrane-associated progesterone receptor component 1 isoform 1
NCBI Official Synonym Full Names
progesterone receptor membrane component 1
NCBI Official Symbol
PGRMC1
NCBI Official Synonym Symbols
MPR; HPR6.6
NCBI Protein Information
membrane-associated progesterone receptor component 1
UniProt Protein Name
Membrane-associated progesterone receptor component 1
Protein Family
UniProt Gene Name
PGRMC1
UniProt Synonym Gene Names
HPR6.6; PGRMC; mPR
UniProt Entry Name
PGRC1_HUMAN
NCBI Description
This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney. [provided by RefSeq, Mar 2010]
Uniprot Description
PGRMC1: Receptor for progesterone. Widely expressed, with highest expression in liver and kidney. Belongs to the cytochrome b5 family. MAPR subfamily.
Protein type: Receptor, misc.; Membrane protein, integral
Chromosomal Location of Human Ortholog: Xq22-q24
Cellular Component: endomembrane system; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; membrane; nucleolus
Molecular Function: heme binding; protein binding; steroid binding
Research Articles on PGRMC1
Similar Products
Product Notes
The PGRMC1 pgrmc1 (Catalog #AAA420498) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-PGRMC1/MPR Antibody reacts with Tested: Human; Expected from sequence similarity: Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PGRMC1/MPR can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 4000. Researchers should empirically determine the suitability of the PGRMC1 pgrmc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: EPKDESARKN D. It is sometimes possible for the material contained within the vial of "PGRMC1/MPR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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