Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human placenta tissue at dilution of 1:100)
Rabbit anti-Human PGAM5 Polyclonal Antibody | anti-PGAM5 antibody
PGAM5 Antibody
Gene Names
PGAM5; BXLBV68
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Immunofluorescence
Purity
>95%, Protein G purified
Synonyms
PGAM5; Polyclonal Antibody; PGAM5 Antibody; Serine/threonine-protein phosphatase PGAM5; mitochondrial; Bcl-XL-binding protein v68; Phosphoglycerate mutase family member 5; anti-PGAM5 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
289
Applicable Applications for anti-PGAM5 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IHC: 1: 20-1: 200
IF: 1: 50-1: 200
IF: 1: 50-1: 200
Immunogen
Recombinant human Serine/threonine-protein phosphatase PGAM5, mitochondrial protein (30-223AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Non-conjugated
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161155 / sc-161156 / sc-161157
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human placenta tissue at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human placenta tissue at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunofluorescent analysis of Hela cells at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunohistochemistry (IHC)
(Immunofluorescent analysis of Hela cells at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-PGAM5 antibody
Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28,020 Da
NCBI Official Full Name
serine/threonine-protein phosphatase PGAM5, mitochondrial isoform 1
NCBI Official Synonym Full Names
PGAM family member 5, mitochondrial serine/threonine protein phosphatase
NCBI Official Symbol
PGAM5
NCBI Official Synonym Symbols
BXLBV68
NCBI Protein Information
serine/threonine-protein phosphatase PGAM5, mitochondrial
UniProt Protein Name
Serine/threonine-protein phosphatase PGAM5, mitochondrial
Protein Family
UniProt Gene Name
PGAM5
UniProt Entry Name
PGAM5_HUMAN
Uniprot Description
PGAM5: Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2- dependent gene expression. Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.3.16; Hydrolase; Membrane protein, integral; Mitochondrial
Chromosomal Location of Human Ortholog: 12q24.33
Cellular Component: mitochondrion
Molecular Function: GTPase activator activity; phosphoric monoester hydrolase activity; protein complex binding; receptor signaling protein serine/threonine phosphatase activity
Research Articles on PGAM5
Similar Products
Product Notes
The PGAM5 pgam5 (Catalog #AAA7050831) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PGAM5 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PGAM5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). IHC: 1: 20-1: 200 IF: 1: 50-1: 200. Researchers should empirically determine the suitability of the PGAM5 pgam5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGAM5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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