Immunohistochemistry (IHC)
(Immunochemical staining of human PGA in human gastric cancer with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections).)
Rabbit anti-Human PGA4 Polyclonal Antibody | anti-PGA4 antibody
Anti-PGA4 Antibody, Rabbit Polyclonal
Gene Names
PGA4; PGA3; PGA5
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
PGA4; Polyclonal Antibody; Anti-PGA4 Antibody; Rabbit Polyclonal; PGA4/Pepsinogen A Antibody; Rabbit PAb; Antigen Affinity Purified; pepsinogen 4; group I (pepsinogen A); Anti-FLJ58952 Antibody; Anti-FLJ77962 Antibody; Anti-PGA3 Antibody; Anti-PGA5 Antibody; anti-PGA4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human PGA4/Pepsinogen A
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-PGA4 antibody
ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
ELISA: 1:5000-1:10,000
IHC-P: 1:2500-1:10,000
IHC-P: 1:2500-1:10,000
Immunogen
Recombinant Human PGA4/Pepsinogen A Protein
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with purified, recombinant Human PGA4/Pepsinogen A (rh PGA4/Pepsinogen A). PGA4/Pepsinogen A specific IgG was purified by Human PGA4/Pepsinogen A affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human PGA in human gastric cancer with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining of human PGA in human gastric cancer with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections).)
Related Product Information for anti-PGA4 antibody
PGA4 (Pepsinogen 4, group I), or Pepsinogen A, is a member of the peptidase A1 family. Pepsin is expressed as a pro-form zymogen, pepsinogen, whose primary structure has an additional 44 amino acids. Pepsin is stored as pepsinogen so it will only be released when needed, and does not digest the body's own proteins in the stomach's lining. Five types of zymogens of pepsins, gastric digestive proteinases, are known: pepsinogens A, B, and F, progastricsin, and prochymosin. There are two major groups of pepsinogen, namely pepsinogen A (PGA) and pepsinogen C (PGC) (or progastricsin), and each frequently has isozymogens. The PGA3, PGA4 and PGA5 genes encode identical human pepsinogen A enzymes.
References
Kageyama T. (2002) Pepsinogens, progastricsins, and prochymosins: structure, function, evolution, and development. Cell Mol Life Sci. 59(2): 288-306.Takahashi K. (1992) Gene structures of pepsinogens A and C. Scand J Clin Lab Invest Suppl. 210: 97-110.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,977 Da
NCBI Official Full Name
pepsin A preproprotein
NCBI Official Synonym Full Names
pepsinogen 4, group I (pepsinogen A)
NCBI Official Symbol
PGA4
NCBI Official Synonym Symbols
PGA3; PGA5
NCBI Protein Information
pepsin A; pepsinogen-3; pepsinogen-4; pepsinogen A4
UniProt Protein Name
Pepsin A-4
Protein Family
UniProt Gene Name
PGA4
UniProt Entry Name
PEPA4_HUMAN
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Product Notes
The PGA4 pga4 (Catalog #AAA8106697) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PGA4 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PGA4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P). ELISA: 1:5000-1:10,000 IHC-P: 1:2500-1:10,000. Researchers should empirically determine the suitability of the PGA4 pga4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGA4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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