Rabbit PERP Polyclonal Antibody | anti-PERP antibody
PERP Polyclonal Antibody
Gene Names
PERP; THW; KCP1; PIGPC1; KRTCAP1; dJ496H19.1; RP3-496H19.1
Applications
Immunoblot, Western Blot
Synonyms
PERP; Polyclonal Antibody; PERP Polyclonal Antibody; anti-PERP antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
PERP [This rabbit antibody recognizes aa 175-193 of human PERP, a plasma membrane protein involved in the p53 network.]
This antibody recognizes human PERP, a plasma membrane protein involved in the p53 network. p53 binds to the promoter of PERP and transcriptionally activates the PERP gene; the translated PERP protein mediates p53-induced apoptosis leading to cell death.
This antibody recognizes human PERP, a plasma membrane protein involved in the p53 network. p53 binds to the promoter of PERP and transcriptionally activates the PERP gene; the translated PERP protein mediates p53-induced apoptosis leading to cell death.
Form/Format
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Sequence Length
193
Applicable Applications for anti-PERP antibody
Immunoblot
Application Notes
Immunoblotting: use at 0.5-1 ug/ml. In immunoblots, a band of 21 kD is detected.
Positive control: A431 cell lysate.
Positive control: A431 cell lysate.
Antigen
Peptide corresponding to aa 175-193 of human PERP. This sequence differs from that of mouse by three amino acids.
Stabilizer
None
Preservatives
0.02% sodium azide
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Product Categories/Family for anti-PERP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,386 Da
NCBI Official Full Name
p53 apoptosis effector related to PMP-22
NCBI Official Synonym Full Names
PERP, TP53 apoptosis effector
NCBI Official Symbol
PERP
NCBI Official Synonym Symbols
THW; KCP1; PIGPC1; KRTCAP1; dJ496H19.1; RP3-496H19.1
NCBI Protein Information
p53 apoptosis effector related to PMP-22; KCP-1; 1110017A08Rik; OTTHUMP00000017293; transmembrane protein THW; p53-induced protein PIGPC1; keratinocyte-associated protein 1; keratinocytes associated protein 1; p53 apoptosis effector related to PMP22
UniProt Protein Name
p53 apoptosis effector related to PMP-22
Protein Family
UniProt Gene Name
PERP
UniProt Synonym Gene Names
KCP1; KRTCAP1; PIGPC1; THW
UniProt Entry Name
PERP_HUMAN
Uniprot Description
PERP: Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway. Belongs to the TMEM47 family.
Protein type: Membrane protein, multi-pass; Mitochondrial; Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 6q24
Cellular Component: Golgi apparatus; desmosome; mitochondrion; integral to plasma membrane
Biological Process: heterotypic cell-cell adhesion; positive regulation of proteolysis
Research Articles on PERP
Similar Products
Product Notes
The PERP perp (Catalog #AAA194324) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PERP can be used in a range of immunoassay formats including, but not limited to, Immunoblot. Immunoblotting: use at 0.5-1 ug/ml. In immunoblots, a band of 21 kD is detected. Positive control: A431 cell lysate. Researchers should empirically determine the suitability of the PERP perp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PERP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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