Chemiluminescence
(Du145 cell lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with MBS618043 (1:5000). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates Peroxiredoxin 4 (~21kD).)
Rabbit anti-Human Peroxiredoxin 4 Polyclonal Antibody | anti-PRDX4 antibody
Peroxiredoxin 4 (Peroxiredoxin-4, PRDX4, PRX-4, Peroxiredoxin IV, Prx-IV, Antioxidant Enzyme AOE372, AOE37-2, Thioredoxin Peroxidase AO372, Thioredoxin-dependent Peroxide Reductase A0372)
Serum
Serum
Dilution: Immunoblot Analysis: A 1:2000-1:10,000 dilution of this lot detected anti-Peroxiredoxin 4 in RIPA lysates from Du145 cells.
Immunocytochemistry: Has been reported by an independent laboratory to detect Peroxiredoxin 4 in TSU-Pr1 cells.
Chemiluminescence
(Du145 cell lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with MBS618043 (1:5000). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates Peroxiredoxin 4 (~21kD).)
Chemiluminescence
(Du145 cell lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with MBS618043 (1:5000). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates Peroxiredoxin 4 (~21kD).)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq]
Uniprot Description
PRDX4: Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation. Belongs to the AhpC/TSA family.
Protein type: Secreted; EC 1.11.1.15; Mitochondrial; Oxidoreductase; Secreted, signal peptide
Chromosomal Location of Human Ortholog: Xp22.11
Cellular Component: extracellular space; smooth endoplasmic reticulum; mitochondrion; cytosol; nucleus
Molecular Function: protein binding; protein homodimerization activity; thioredoxin peroxidase activity
Biological Process: protein maturation via protein folding; extracellular matrix organization and biogenesis; 4-hydroxyproline metabolic process; cell redox homeostasis; male gonad development; spermatogenesis; I-kappaB phosphorylation
Research Articles on PRDX4
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Product Notes
The PRDX4 prdx4 (Catalog #AAA618043) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Peroxiredoxin 4 (Peroxiredoxin-4, PRDX4, PRX-4, Peroxiredoxin IV, Prx-IV, Antioxidant Enzyme AOE372, AOE37-2, Thioredoxin Peroxidase AO372, Thioredoxin-dependent Peroxide Reductase A0372) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Peroxiredoxin 4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). Suitable for use in Western Blot and Immunocytochemistry. Dilution: Immunoblot Analysis: A 1:2000-1:10,000 dilution of this lot detected anti-Peroxiredoxin 4 in RIPA lysates from Du145 cells. Immunocytochemistry: Has been reported by an independent laboratory to detect Peroxiredoxin 4 in TSU-Pr1 cells. Researchers should empirically determine the suitability of the PRDX4 prdx4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Peroxiredoxin 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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