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Rabbit anti-Mouse Period Clock Protein 1 Polyclonal Antibody | anti-per antibody

Period Clock Protein 1 (Per1, RIGUI)

Gene Names
per; CG2647; Clk; clk-6; DmelCG2647; dmper; dper; dPER; EG:155E2.4; mel_per; Per; PER
Reactivity
Mouse
Applications
ELISA, Western Blot
Purity
Serum
Serum
Synonyms
Period Clock Protein 1; Polyclonal Antibody; Period Clock Protein 1 (Per1; RIGUI); Anti -Period Clock Protein 1 (Per1; anti-per antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes Period Clock Protein 1. No significant homology is seen with Per2, Per 3, dPER or other known proteins. Species homology: human Per1 (93%).
Purity/Purification
Serum
Serum
Form/Format
Supplied as a liquid, neat serum, 0.05% sodium azide, 40% glycerol.
Applicable Applications for anti-per antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA, Western Blot.
Dilution: Western Blot: 1:1000-1:5000.
ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well.
Immunogen
A 16-aa peptide internal sequence mapping downstream of the SG repeat of mouse Per 1 (KLH conjugated).
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-per antibody
Several endogenous factors have been linked to rhythmicity or circadian behavior of living organisms. In Drosophila, the genes period (dPer) and timeless (tim), and in Neurospora frequency (frq), have been proposed to be responsible for their circadian rhythm. Recently human and mouse genes encoding a basichelix-loop-helix (bHLH) and Per-ARNT-Sim (PAS)-domain with significant similarity to the Drosophila Period have been reported. The cDNA sequences of hPER and mPer1 (also named RIGUI) are predicted to encode for proteins of length 1290 and 1291 amino acids respectively. Homologues of mPer1 designated Per 2 (1257aa) and Per3 (1113aa) have also been cloned. Both Per1 and Per2 levels show circadian rhythm in the SCN and eyes. It has been suggested that mPer regulates neuronal activity in the SCN. Using genetic approach, a single mutation (A to T in the Clock gene affects circadian rhythmicity in mice. Clock has been mapped to chromosome 5. Mouse Clock encodes a transcription factor, a single polypeptide chain of 855aa (predicted calculated mol wt ~97kD; pI 6.52; hClock, 846aa). Clock is abundantly expressed in brain (SCN, pyrifom cortex, hippocampus) as well as in other tissues (eye, total brain, tested, ovaries, liver, heart, lung, and kidney). Although, Clock is constitutively expressed (not rhythmic) in the SCN, it may still be an important component of circadian machinery.
Product Categories/Family for anti-per antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
period, isoform B
NCBI Official Synonym Full Names
period
NCBI Official Symbol
per
NCBI Official Synonym Symbols
CG2647; Clk; clk-6; DmelCG2647; dmper; dper; dPER; EG:155E2.4; mel_per; Per; PER
NCBI Protein Information
CG2647 gene product from transcript CG2647-RA; CG2647-PA; CG2647-PB; PERIOD; clock; clock-6; dperiod; per-PA; per-PB; period clock protein
Protein Family

Research Articles on per

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Product Notes

The per (Catalog #AAA610600) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Period Clock Protein 1 (Per1, RIGUI) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Period Clock Protein 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA, Western Blot. Dilution: Western Blot: 1:1000-1:5000. ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well. Researchers should empirically determine the suitability of the per for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Period Clock Protein 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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