Rabbit anti-Human PELP1 Polyclonal Antibody | anti-PELP1 antibody

PELP1, CT (Proline-, Glutamic Acid-and Leucine-rich Protein 1, H6 Family Homeobox 3, HMX3, Modulator of Non-genomic Activity of Estrogen Receptor, MNAR, NKX5.1, Nkx5-1, NKX-5.1, P160, Transcription Factor HMX3) (PE)

Cat. Num. AAA6492644

• Gene Names: Hmx3; Nkx5-1; Nkx5.1; Nkx-5.1
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Immunoaffinity chromatography.
• Synonyms: PELP1; Polyclonal Antibody; CT (Proline-; Glutamic Acid-and Leucine-rich Protein 1; H6 Family Homeobox 3; HMX3; Modulator of Non-genomic Activity of Estrogen Receptor; MNAR; NKX5.1; Nkx5-1; NKX-5.1; P160; Transcription Factor HMX3) (PE); Proline; Glutamate and Leucine Rich Protein 1; Homeobox Protein H6 Family Member 3; Homeobox Protein HMX3; Homeobox Protein Nkx-5.1; anti-PELP1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human Hmx3.
• Purity/Purification: Purified by Immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-PELP1 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:50-1:100; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: Synthetic peptide selected from the C-terminal region of mouse Hmx3 (KLH).
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of anti-Mouse Hmx3 Antibody (C-term) in mouse stomach tissue lysates (35ug/lane). Hmx3(arrow) was detected using the purified Pab)

Product Categories/Family for anti-PELP1 antibody

Antibodies; Receptors; Estrogen

References

1. Mennerich D., Hoffmann S., Biol. Chem. 380:1041-1048(1999). 2. Rinkwitz-Brandt S., Justus M., Mech. Dev. 52:371-381(1995). 3. Rinkwitz-Brandt S., Arnold H.H., Bober E.Hear. Res. 99:129-138(1996). 4. Amendt B.A., Sutherland L.B., J. Biol. Chem. 274:11635-11642(1999).

NCBI and Uniprot Product Information

• NCBI GI #: 157787085
• NCBI GeneID: 15373
• NCBI Accession #: NP_032283
• NCBI GenBank Nucleotide #: NM_008257
• UniProt Accession #: P42581
• Molecular Weight: 38kDa
• NCBI Official Full Name: homeobox protein HMX3
• NCBI Official Synonym Full Names: H6 homeobox 3
• NCBI Official Symbol: Hmx3
• NCBI Official Synonym Symbols: Nkx5-1; Nkx5.1; Nkx-5.1
• NCBI Protein Information: homeobox protein HMX3
• UniProt Protein Name: Homeobox protein HMX3
• Protein Family: Proline-, glutamic acid- and leucine-rich protein
• UniProt Gene Name: Hmx3
• UniProt Synonym Gene Names: Nkx-5.1; Nkx5-1
• UniProt Entry Name: HMX3_MOUSE

Uniprot Description

HMX3: Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS. Belongs to the HMX homeobox family.

Protein type: DNA-binding

Cellular Component: nucleus

Molecular Function: DNA binding; sequence-specific DNA binding

Biological Process: nervous system development; inner ear morphogenesis; maternal process involved in pregnancy; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development; brain development; cell differentiation; neuromuscular process controlling balance; embryo implantation