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Western Blot (WB) (Lane 1:Rat Brain Tissue Lysate; Lane 2:Rat Liver Tissue Lysate; Lane 3:SMMC Cell Lysate; Lane 4:HEPA Cell Lysate; Lane 5:293T Cell Lysate; Lane 6:HELA Cell Lysate)

Rabbit PDPN Polyclonal Antibody | anti-PDPN antibody

PDPN Antibody

Gene Names
PDPN; T1A; GP36; GP40; Gp38; OTS8; T1A2; TI1A; T1A-2; AGGRUS; HT1A-1; PA2.26
Applications
Western Blot
Purity
Affinity Chromatography
Synonyms
PDPN; Polyclonal Antibody; PDPN Antibody; Affinity Purified Mouse Polyclonal PDPN Antibody; Polyclonal PDPN antibody; Anti-PDPN antibody; TIA2. antibody; T1A antibody; gp 36 antibody; Lung type I cell membrane associated glycoprotein T1A 2 antibody; Lung type-I cell membrane-associated glycoprotein isoform a antibody; PDPN antibody; GP40 antibody; OTTHUMP00000044504 antibody; Glycoprotein 36 antibody; Glycoprotein 36 KD antibody; GP 38 antibody; HT1A-1 antibody; HT1A1 antibody; T1A-2 antibody; PA2.26 antigen antibody; OTS8 antibody; Lung type I cell membrane associated glycoprotein antibody; T1 alpha GENE antibody; T1 alpha antibody; GP 40 antibody; GP36 antibody; Lung type-I cell membrane-associated glycoprotein isoform a AGGRUS antibody; OTTHUMP00000009640 antibody; PA2.26 antibody; hT1alpha2 antibody; Podoplanin antibody; Gp38 antibody; Lung type I cell membrane associated glycoprotein isoform a antibody; OTS 8 antibody; TIA 2 antibody; HT1A 1 antibody; hT1alpha1 antibody; anti-PDPN antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Lyophilized Form
Sequence Length
118
Applicable Applications for anti-PDPN antibody
Western Blot (WB)
Immunogen
PDPN antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of rat PDPN, different from the related Rabbit sequence by one amino acid, as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.

Western Blot (WB)

(Lane 1:Rat Brain Tissue Lysate; Lane 2:Rat Liver Tissue Lysate; Lane 3:SMMC Cell Lysate; Lane 4:HEPA Cell Lysate; Lane 5:293T Cell Lysate; Lane 6:HELA Cell Lysate)

Western Blot (WB) (Lane 1:Rat Brain Tissue Lysate; Lane 2:Rat Liver Tissue Lysate; Lane 3:SMMC Cell Lysate; Lane 4:HEPA Cell Lysate; Lane 5:293T Cell Lysate; Lane 6:HELA Cell Lysate)
Related Product Information for anti-PDPN antibody
Podoplanin (PDPN) is a small mucin-like transmembrane protein, widely expressed in various specialized cell types throughout the body. This is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character.
Product Categories/Family for anti-PDPN antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
podoplanin isoform d
NCBI Official Synonym Full Names
podoplanin
NCBI Official Symbol
PDPN
NCBI Official Synonym Symbols
T1A; GP36; GP40; Gp38; OTS8; T1A2; TI1A; T1A-2; AGGRUS; HT1A-1; PA2.26
NCBI Protein Information
podoplanin
UniProt Protein Name
Podoplanin
Protein Family
UniProt Gene Name
PDPN
UniProt Synonym Gene Names
GP36; Gp36; T1A
UniProt Entry Name
PDPN_HUMAN

NCBI Description

This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

PDPN: May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels. Belongs to the podoplanin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.21

Cellular Component: ruffle; filopodium membrane; lamellipodium; integral to plasma membrane; microvillus membrane; apical plasma membrane; plasma membrane; filopodium; external side of plasma membrane

Molecular Function: folic acid transporter activity; water transporter activity; water channel activity; amino acid transmembrane transporter activity

Biological Process: nervous system development; water transport; cell morphogenesis; positive regulation of cell motility; signal transduction; prostaglandin metabolic process; folic acid transport; cell proliferation; regulation of cell shape; cell-cell adhesion; response to hyperoxia; amino acid transport; lymphangiogenesis; tube morphogenesis; inflammatory response; alveolus development; lung development; positive regulation of cell migration

Research Articles on PDPN

Similar Products

Product Notes

The PDPN pdpn (Catalog #AAA5312970) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PDPN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the PDPN pdpn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDPN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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