Rabbit PDE4D1 Polyclonal Antibody | anti-PDE4D1 antibody
PDE4D1 Antibody BIOTIN-Conjugated
Reactivity
Chicken, Mouse, Rat
Applications
ELISA, Immunoprecipitation, Western Blot
Synonyms
PDE4D1; Polyclonal Antibody; PDE4D1 Antibody BIOTIN-Conjugated; cAMP specific 3'; 5' cyclic phosphodiesterase 4D; DKFZp686M11213; 5''-cyclic phosphodiesterase 4D; cAMP specific phosphodiesterase 4D; cAMP specific phosphodiesterase PDE4D; DPDE 3; Dunce like phosphodiesterase E3; FLJ97311; HSPDE4D; PDE 43; PDE4DN2; Phosphodiesterase E3 dunce homolog Drosophila; STRK1 antibody; anti-PDE4D1 antibody
Host
Rabbit
Reactivity
Chicken, Mouse, Rat
Clonality
Polyclonal
Specificity
Will not cross react with other PDE4D variants or other PDE family members.
Form/Format
BIOTIN-Conjugated
Concentration
0.73 ug/ul in antibody stabilization buffer (varies by lot)
Applicable Applications for anti-PDE4D1 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:150
Western Blot: 1:500
ELISA: 1:10,000
Immunoprecipitation: 1:150
Western Blot: 1:500
Immunogen
Synthetic peptide from unique region near N-terminus of PDE4D1 variant.
Expression
Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.
Molecular Function
Hydrolase, 3', 5'-cyclic-AMP phosphodiesterase activity, cAMP binding
Structure
Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Isoform 3 is part of a ternary complex containing PRKAR2A, PRKAR2B and AKAP9. Interacts with PDE4DIP. Identified in a complex composed of RYR1, PDE4D, PKA, FKBP1A and protein phosphatase 1 (PP1).
Subcellular Location
Apical cell membrane, Cytoplasm, Membrane
Preparation and Storage
-20 degree C for long term storage
Related Product Information for anti-PDE4D1 antibody
BIOTIN-Conjugated Phosphodiesterase 4D1 Antibody
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
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Product Notes
The PDE4D1 (Catalog #AAA543515) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDE4D1 Antibody BIOTIN-Conjugated reacts with Chicken, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PDE4D1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). Dot Blot: 1:10,000 ELISA: 1:10,000 Immunoprecipitation: 1:150 Western Blot: 1:500. Researchers should empirically determine the suitability of the PDE4D1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDE4D1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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