Rabbit anti-Human PDCL3 Polyclonal Antibody | anti-PDCL3 antibody

PDCL3, NT (PDCL3, VIAF1, Phosducin-like protein 3, HTPHLP, PhPL3, Viral IAP-associated factor 1) (PE)

Cat. Num. AAA6332066

• Gene Names: PDCL3; VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: PDCL3; Polyclonal Antibody; NT (PDCL3; VIAF1; Phosducin-like protein 3; HTPHLP; PhPL3; Viral IAP-associated factor 1) (PE); Viral IAP-associated factor 1; anti-PDCL3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-PDCL3 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: PDCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-68 amino acids from the N-terminal region of human PDCL3.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(PDCL3 Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the PDCL3 antibody detected the PDCL3 protein (arrow).)

Related Product Information for anti-PDCL3 antibody

This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G proteins. [provided by RefSeq].

Product Categories/Family for anti-PDCL3 antibody

Antibodies; Proteins

References

Stirling, P.C., et al. Mol. Biol. Cell 18(6):2336-2345(2007). Lamesch, P., et al. Genomics 89(3):307-315(2007). Wilkinson, J.C., et al. J. Biol. Chem. 279(49):51091-51099(2004). Lopez, P., et al. J. Biol. Chem. 278(3):1751-1757(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 13129044
• NCBI GeneID: 79031
• NCBI Accession #: NP_076970.1
• NCBI GenBank Nucleotide #: NM_024065.4
• UniProt Accession #: Q9H2J4; Q53S68; B2RA00
• Molecular Weight: 27,614 Da
• NCBI Official Full Name: phosducin-like protein 3
• NCBI Official Synonym Full Names: phosducin like 3
• NCBI Official Symbol: PDCL3
• NCBI Official Synonym Symbols: VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A
• NCBI Protein Information: phosducin-like protein 3
• UniProt Protein Name: Phosducin-like protein 3
• Protein Family: Phosducin-like protein
• UniProt Gene Name: PDCL3
• UniProt Synonym Gene Names: PhLP2A; VIAF1; VIAF-1
• UniProt Entry Name: PDCL3_HUMAN

Uniprot Description

PDCL3: Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination. Belongs to the phosducin family.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 2q11.2

Cellular Component: cytoplasm

Molecular Function: protein binding; vascular endothelial growth factor receptor 2 binding

Biological Process: positive regulation of angiogenesis; protein folding; viral reproduction; apoptosis; positive regulation of endothelial cell proliferation; angiogenesis; regulation of peptidyl-tyrosine phosphorylation