Western Blot (WB)
(WB Suggested Anti-PCTK1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Human Small Intestine)
Rabbit PCTK1 Polyclonal Antibody | anti-CDK16 antibody
PCTK1 antibody - N-terminal region
Gene Names
CDK16; PCTK1; PCTAIRE; PCTAIRE1; PCTGAIRE
Reactivity
Cow, Dog, Human, Mouse, Rat, Zebrafish
Applications
Western Blot
Purity
Affinity Purified
Synonyms
PCTK1; Polyclonal Antibody; PCTK1 antibody - N-terminal region; anti-CDK16 antibody
Host
Rabbit
Reactivity
Cow, Dog, Human, Mouse, Rat, Zebrafish
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTR
Sequence Length
496
Applicable Applications for anti-CDK16 antibody
Western Blot (WB)
Homology
Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 91%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human PCTK1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(WB Suggested Anti-PCTK1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Human Small Intestine)
Western Blot (WB)
(WB Suggested Anti-PCTK1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Human Small Intestine)
Related Product Information for anti-CDK16 antibody
This is a rabbit polyclonal antibody against PCTK1. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: PCTK1 may play a role in signal transduction cascades in terminally differentiated cells.The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells. This gene is thought to escape X inactivation. Two transcript variants encoding the same protein have been found for this gene.
Target Description: PCTK1 may play a role in signal transduction cascades in terminally differentiated cells.The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells. This gene is thought to escape X inactivation. Two transcript variants encoding the same protein have been found for this gene.
Product Categories/Family for anti-CDK16 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
56kDa
NCBI Official Full Name
cyclin-dependent kinase 16 isoform 1
NCBI Official Synonym Full Names
cyclin dependent kinase 16
NCBI Official Symbol
CDK16
NCBI Official Synonym Symbols
PCTK1; PCTAIRE; PCTAIRE1; PCTGAIRE
NCBI Protein Information
cyclin-dependent kinase 16
UniProt Protein Name
Cyclin-dependent kinase 16
Protein Family
UniProt Gene Name
CDK16
UniProt Synonym Gene Names
PCTAIRE1; PCTK1
NCBI Description
The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2009]
Uniprot Description
Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser-336' (in vitro).
Research Articles on CDK16
1. CDK16 negatively modulates p53 signaling pathway to promote radioresistance in lung cancer cells.
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Product Notes
The CDK16 cdk16 (Catalog #AAA3224372) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PCTK1 antibody - N-terminal region reacts with Cow, Dog, Human, Mouse, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's PCTK1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the CDK16 cdk16 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: MDRMKKIKRQ LSMTLRGGRG IDKTNGAPEQ IGLDESGGGG GSDPGEAPTR. It is sometimes possible for the material contained within the vial of "PCTK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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