Immunohistochemistry (IHC)
(Staining with Mouse Pcp2 Antibody (C-term) (MBS9202206) was colocalized with GFP in most of the Purkinje cells with low background in 1:500 dilution condition. Intensity of PCP2 staining was not necessarily corresponded to the intensity of GFP, and there are a few GFP positive, not stained with pcp2 antibody, cells. In dendrites and axons of Purkinje cells, most of fibers stained with PCP-2 antibodies were colocalized with GFP.)
Rabbit anti-Mouse Pcp2 Polyclonal Antibody | anti-Pcp2 antibody
Mouse Pcp2 Antibody (C-term)
Gene Names
Pcp2; L7; Pcp-2
Reactivity
Mouse
Applications
ELISA, Immunohistochemistry
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Pcp2; Polyclonal Antibody; Mouse Pcp2 Antibody (C-term); Purkinje cell protein 2; Protein PCD-5; Purkinje cell-specific protein L7; Pcp-2; anti-Pcp2 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse Pcp2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-120 amino acids from the C-terminal region of mouse Pcp2.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Sequence Length
120
Applicable Applications for anti-Pcp2 antibody
ELISA (EIA), Immunohistochemistry Paraffin (IHC-P)
Application Notes
IHC-P ~~ 1:500
Tissue Location
Cerebellum (Purkinje cells) and retinal bipolar neurons.
Function
May function as a cell-type specific modulator for G protein - mediated cell signaling.
Antigen Region
91-120
Preparation and Storage
Maintain refrigerated at 2 - 8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Immunohistochemistry (IHC)
(Staining with Mouse Pcp2 Antibody (C-term) (MBS9202206) was colocalized with GFP in most of the Purkinje cells with low background in 1:500 dilution condition. Intensity of PCP2 staining was not necessarily corresponded to the intensity of GFP, and there are a few GFP positive, not stained with pcp2 antibody, cells. In dendrites and axons of Purkinje cells, most of fibers stained with PCP-2 antibodies were colocalized with GFP.)
Immunohistochemistry (IHC)
(Staining with Mouse Pcp2 Antibody (C-term) (MBS9202206) was colocalized with GFP in most of the Purkinje cells with low background in 1:500 dilution condition. Intensity of PCP2 staining was not necessarily corresponded to the intensity of GFP, and there are a few GFP positive, not stained with pcp2 antibody, cells. In dendrites and axons of Purkinje cells, most of fibers stained with PCP-2 antibodies were colocalized with GFP.)
Related Product Information for anti-Pcp2 antibody
Pcp2 may function as a cell-type specific modulator for G protein-mediated cell signaling. This protein exhibits tissue specificity for cerebellum (Purkinje cells) and retinal bipolar neurons.
References
Guan,J. et al. Biochem. J. 392 (PT 2), 389-397 (2005) Saito,H. et al. Biochem. Biophys. Res. Commun. 331 (4), 1216-1221 (2005) Redd,K.J. et al. J. Neurosci. Res. 70 (5), 631-637 (2002) Zhang,X. et al. Brain Res. Mol. Brain Res. 105 (1-2), 1-10 (2002) Luo,Y. et al. J. Biol. Chem. 274 (16), 10685-10688 (1999)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated MW: 13054
NCBI Official Full Name
Purkinje cell protein 2 isoform 2
NCBI Official Synonym Full Names
Purkinje cell protein 2 (L7)
NCBI Official Symbol
Pcp2
NCBI Official Synonym Symbols
L7; Pcp-2
NCBI Protein Information
Purkinje cell protein 2
UniProt Protein Name
Purkinje cell protein 2
Protein Family
UniProt Gene Name
Pcp2
UniProt Synonym Gene Names
Pcp-2
UniProt Entry Name
PCP2_MOUSE
Uniprot Description
PCP2: May function as a cell-type specific modulator for G protein-mediated cell signaling.
Cellular Component: cell soma
Molecular Function: guanyl-nucleotide exchange factor activity; GTPase regulator activity
Biological Process: rhodopsin mediated signaling; positive regulation of GTPase activity
Research Articles on Pcp2
Similar Products
Product Notes
The Pcp2 pcp2 (Catalog #AAA9202206) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mouse Pcp2 Antibody (C-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Pcp2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry Paraffin (IHC-P). IHC-P ~~ 1:500. Researchers should empirically determine the suitability of the Pcp2 pcp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pcp2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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