Western Blot (WB)
(Western Blot analysis of PCDHB2 expression in transfected 293T cell line by PCDHB2 polyclonal antibody. Lane1:PCDHB2 transfected lysate (87.78kD). Lane2:Non-transfected lysate.)
Mouse anti-Human PCDHB2 Polyclonal Antibody | anti-PCDHB2 antibody
PCDHB2 (Protocadherin beta-2, PCDH-beta-2, MGC111392)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of PCDHB2 expression in transfected 293T cell line by PCDHB2 polyclonal antibody. Lane1:PCDHB2 transfected lysate (87.78kD). Lane2:Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of PCDHB2 expression in transfected 293T cell line by PCDHB2 polyclonal antibody. Lane1:PCDHB2 transfected lysate (87.78kD). Lane2:Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008]
Uniprot Description
PCDHB2: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Protein type: Membrane protein, integral; Cell adhesion
Chromosomal Location of Human Ortholog: 5q31
Cellular Component: integral to plasma membrane; integral to membrane
Molecular Function: calcium ion binding
Biological Process: synaptic transmission; nervous system development; synaptogenesis; calcium-dependent cell-cell adhesion; homophilic cell adhesion; cell adhesion
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Product Notes
The PCDHB2 pcdhb2 (Catalog #AAA642067) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PCDHB2 (Protocadherin beta-2, PCDH-beta-2, MGC111392) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PCDHB2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the PCDHB2 pcdhb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MEAGEGKERV PKQRQVLIFF VLLGIAQASC QPRHYSVAEE TESGSFVANL LKDLGLEIGE LAVRGARVVS KGKKMHLQFD RQTGDLLLNE KLDREELCGP TEPCVLPFQV LLENPLQFFQ AELRIRDVND HSPVFLDKEI LLKIPESITP GTTFLIERAQ DLDVGTNSLQ NYTISPNFHF HLNLQDSLDG IILPQLVLNR ALDREEQPEI RLTLTALDGG SPPRSGTALV RIEVVDINDN VPEFAKLLYE VQIPEDSPVG SQVAIVSARD LDIGTNGEIS YAFSQASEDI RKTFRLSAKS GELLLRQKLD FESIQTYTVN IQATDGGGLS GTCVVFVQVM DLNDNPPELT MSTLINQIPE NLQDTLIAVF SVSDPDSGDN GRMVCSIQDD LPFFLKPSVE NFYTLVISTA LDRETRSEYN ITITVTDFGT PRLKTEHNIT VLVSDVNDNA PAFTQTSYTL FVRENNSPAL HIGSVSATDR DSGTNAQVTY SLLPPQDPHL PLASLVSINA DNGHLFALQS LDYEALQAFE FRVGAADRGS PALSSEALVR VLVLDANDNS PFVLYPLQNG SAPCTELVPR AAEPGYLVTK VVAVDGDSGQ NAWLSYQLLK ATEPGLFGVW AHNGEVRTAR LLRERDAAKQ RLVVLVKDNG EPPRSATATL HVLLVDGFSQ PYLLLPEAAP AQAQADLLTV YLVVALASVS SLFLFSVLLF VAVRLCRRSR AASVGRCSVP EGPFPGQMVD VSGTGTLSQS YQYEVCLTGE SGTNEFKFLK PIIPNFVAQG AERVSEANPS FRKSFEFT. It is sometimes possible for the material contained within the vial of "PCDHB2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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