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Goat Patched 1 Polyclonal Antibody | anti-ptc1 antibody

Goat anti-Patched 1 (zebrafish) Antibody

Gene Names
ptch2; ptc1; ptc-1; ptch1
Reactivity
Tested: Zebrafish; Expected from sequence similarity: Zebrafish
Applications
ELISA, Immunofluorescence
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
Patched 1; Polyclonal Antibody; Goat anti-Patched 1 (zebrafish) Antibody; ptc1; patched 1; ptc-1; etID309849.2; patched1; ptc1 antibody; patched 1 antibody; ptc-1 antibody; etID309849.2 antibody; patched1 antibody; Patched 1 (zebrafish); anti-ptc1 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Tested: Zebrafish; Expected from sequence similarity: Zebrafish
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
QTGSKKEPFNYSQ
Sequence Length
1220
Applicable Applications for anti-ptc1 antibody
Peptide ELISA (EIA), Immunofluorescence (IF)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Immunofluorescence: This product has been successfully used in IF studies of zebrafish tumors (Ju et al, Mol Cancer.2009 Jun 25;8: 40.; PMID: 19555497). Recommended concentration: 1-3ug/ml.
Immunogen
Peptide with sequence C-QTGSKKEPFNYSQ, from the internal region of the protein sequence according to NP_571063.1.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
135,544 Da
NCBI Official Full Name
protein patched homolog 1
NCBI Official Synonym Full Names
patched 2
NCBI Official Symbol
ptch2
NCBI Official Synonym Symbols
ptc1; ptc-1; ptch1
NCBI Protein Information
protein patched homolog 1
UniProt Protein Name
Protein patched homolog 1
Protein Family
UniProt Gene Name
ptch1
UniProt Synonym Gene Names
ptc1; PTC1; Patched 1
UniProt Entry Name
PTC1_DANRE

Uniprot Description

Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal ().

Research Articles on ptc1

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Product Notes

The ptc1 ptch1 (Catalog #AAA421171) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Patched 1 (zebrafish) Antibody reacts with Tested: Zebrafish; Expected from sequence similarity: Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's Patched 1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Immunofluorescence (IF). Peptide ELISA: Antibody detection limit dilution 1: 32000. Immunofluorescence: This product has been successfully used in IF studies of zebrafish tumors (Ju et al, Mol Cancer.2009 Jun 25;8: 40.; PMID: 19555497). Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the ptc1 ptch1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: QTGSKKEPFN YSQ. It is sometimes possible for the material contained within the vial of "Patched 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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