Rabbit PAP2 Polyclonal Antibody | anti-PAP2 antibody

Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast) PAP2 Polyclonal Antibody

• Gene Names: PAP2; TRF4
• Reactivity: Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: PAP2; Polyclonal Antibody; Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast) PAP2 Polyclonal Antibody; PAP2 Antibody; Poly(A; RNA polymerase protein 2; EC 2.7.7.-; DNA polymerase kappa; DNA polymerase sigma; Topoisomerase 1-related protein TRF4; PAP2 TRF4 YOL115W HRC584 O0716; anti-PAP2 antibody

• Host: Rabbit
• Reactivity: Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-PAP2 antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PAP2 protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 6324457
• NCBI GeneID: 854034
• NCBI Accession #: NP_014526.1
• NCBI GenBank Nucleotide #: NM_001183369.1
• UniProt Accession #: P53632; D6W1V2
• Molecular Weight: 66,031 Da
• NCBI Official Full Name: non-canonical poly(A) polymerase PAP2
• NCBI Official Symbol: PAP2
• NCBI Official Synonym Symbols: TRF4
• NCBI Protein Information: non-canonical poly(A) polymerase PAP2
• UniProt Protein Name: Poly(A) RNA polymerase protein 2
• Protein Family: Poly(A) RNA polymerase protein
• UniProt Gene Name: PAP2
• UniProt Synonym Gene Names: TRF4

Uniprot Description

Catalytic subunit of the TRAMP complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism limiting inappropriate expression of genetic information. Polyadenylation is required for the degradative activity of the exosome on several of its nuclear RNA substrates like cryptic transcripts generated by RNA polymerase II and III, or hypomethylated pre-tRNAi-Met. Polyadenylates RNA processing and degradation intermediates of snRNAs, snoRNAs and mRNAs that accumulate in strains lacking a functional exosome. TRF4 is also required for proper nuclear division in mitosis, DNA damage repair and sister chromatid cohesion. Involved in the regulation of histone mRNA levels. May mediate mitotic chromosome condensation.