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Rabbit PAOX Polyclonal Antibody | anti-PAOX antibody

PAOX

Gene Names
PAOX; PAO
Reactivity
Human
Predicted: Rat, Mouse
Applications
ELISA, Western Blot
Purity
Purified By Antigen Affinity Column
Synonyms
PAOX; Polyclonal Antibody; DKFZp434J245; MGC45464; PAO; RP11-122K13.11; anti-PAOX antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
486
Applicable Applications for anti-PAOX antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:20,000-80,000
WB: 1:200-1,000
Immunogen
Recombinant fragment corresponding to 171-408aa of human PAOX.
Cellular Localization
Cytoplasm, Peroxisome
Related Product Information for anti-PAOX antibody
Homo sapiens polyamine oxidase (exo-N4-amino), mRNA
References
Shin SY, Fauman EB, Petersen AK. et al. An atlas of genetic influences on human blood metabolites. Nat Genet. 46(6):543-50 (2014)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
56KD
NCBI Official Full Name
peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 4
NCBI Official Synonym Full Names
polyamine oxidase
NCBI Official Symbol
PAOX
NCBI Official Synonym Symbols
PAO
NCBI Protein Information
peroxisomal N(1)-acetyl-spermine/spermidine oxidase
UniProt Protein Name
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
UniProt Gene Name
PAOX
UniProt Synonym Gene Names
PAO

Uniprot Description

Flavoenzyme which catalyzes the oxidation of N1-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N1-acetylspermidine to putrescine. Substrate specificity: N1-acetylspermine = N1-acetylspermidine > N1,N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.MiscellaneousOxidizes N1-acetylated polyamines on the exo-side of their N4-amino groups. Plant PAO oxidizes spermine on the endo-side of the N4-nitrogen ().

Research Articles on PAOX

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Product Notes

The PAOX paox (Catalog #AAA8562052) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PAOX reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PAOX can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:20,000-80,000 WB: 1:200-1,000. Researchers should empirically determine the suitability of the PAOX paox for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAOX, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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