Rabbit Pancreatic Lipase Polyclonal Antibody | anti-PNLIP antibody

Pancreatic Lipase Rabbit Polyclonal

Cat. Num. AAA7602365

• Gene Names: PNLIP; PL; PTL; PNLIPD
• Reactivity: Human, Mouse, Rat; other species are not tested.
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: Pancreatic Lipase; Polyclonal Antibody; Pancreatic Lipase Rabbit Polyclonal; Lipase; PL; PNLIP; PTL; anti-PNLIP antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat; other species are not tested.
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Please decide the specificity by homology
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 465

• Applicable Applications for anti-PNLIP antibody: ELISA, WB, IHC, IF
• Application Notes: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
• Immunogen: Pancreatic lipase
• Calculated MW: 55 kDa
• Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Preparation and Storage: -20°C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human pancreas cancer using MBS7602365 (PNLIP antibody) at dilution of 1:50)

Western Blot (WB)

(human pancreas tissue were subjected to SDS PAGE followed by western blot with MBS7602365 (PNLIP antibody) at dilution of 1:1000)

Related Product Information for anti-PNLIP antibody

This gene encodes a member of the lipase family of proteins. The encoded enzyme is secreted by the pancreas and hydrolyzes triglycerides in the small intestine, and is essential for the efficient digestion of dietary fats. Inhibition of the encoded enzyme may prevent high-fat diet-induced obesity in mice and result in weight loss in human patients with obesity. Mutations in this gene cause congenital pancreatic lipase deficiency, a rare disorder characterized by steatorrhea.

NCBI and Uniprot Product Information

• NCBI GI #: 1304379
• NCBI GeneID: 5406
• UniProt Accession #: P16233; Q5VSQ2
• NCBI Official Full Name: pancreatic lipase
• NCBI Official Synonym Full Names: pancreatic lipase
• NCBI Official Symbol: PNLIP
• NCBI Official Synonym Symbols: PL; PTL; PNLIPD
• NCBI Protein Information: pancreatic triacylglycerol lipase
• UniProt Protein Name: Pancreatic triacylglycerol lipase
• Protein Family: Pancreatic lipase-related protein
• UniProt Gene Name: PNLIP
• UniProt Synonym Gene Names: PL; PTL; Pancreatic lipase
• UniProt Entry Name: LIPP_HUMAN

NCBI Description

This gene is a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. This gene is expressed specifically in the pancreas. [provided by RefSeq, Jul 2008]

Uniprot Description

PNLIP: a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. expressed specifically in the pancreas. [provided by RefSeq, Jul 2008]

Protein type: Hydrolase; Secreted, signal peptide; Secreted; EC 3.1.1.3; Lipid Metabolism - glycerolipid

Chromosomal Location of Human Ortholog: 10q26.1

Cellular Component: extracellular region

Molecular Function: metal ion binding; triacylglycerol lipase activity

Biological Process: cholesterol absorption; lipid catabolic process; lipid digestion; retinoid metabolic process

Disease: Pancreatic Lipase Deficiency