Western Blot (WB)
(Western blot analysis of PAN3 Antibody (C-term) in Jurkat cell line lysates (35ug/lane). PAN3 (arrow) was detected using the purified Pab.)
Rabbit anti-Human PAN3 Polyclonal Antibody | anti-PAN3 antibody
PAN3, CT (PAN3, PAB-dependent poly(A)-specific ribonuclease subunit 3) (AP)
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of PAN3 Antibody (C-term) in Jurkat cell line lysates (35ug/lane). PAN3 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of PAN3 Antibody (C-term) in Jurkat cell line lysates (35ug/lane). PAN3 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(PAN3 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PAN3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(PAN3 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PAN3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(PAN3 Antibody (C-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(PAN3 Antibody (C-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
Uniprot Description
PAN3: Functions in cytoplasmic mRNA decay. As part of the Pan nuclease complex, recruits polyadenylate-binding protein which in turn stimulates PAN2 nuclease activity. Belongs to the protein kinase superfamily. 4 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 13q12.2
Cellular Component: cytosol
Molecular Function: protein binding; poly(A)-specific ribonuclease activity; metal ion binding; transferase activity, transferring phosphorus-containing groups; ATP binding
Biological Process: deadenylation-dependent decapping; poly(A) tail shortening; gene expression; protein targeting; mRNA catabolic process, deadenylation-dependent decay
Research Articles on PAN3
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Product Notes
The PAN3 pan3 (Catalog #AAA6330659) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PAN3, CT (PAN3, PAB-dependent poly(A)-specific ribonuclease subunit 3) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PAN3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB). IHC: 1:50-100 ELISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PAN3 pan3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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