Rabbit anti-Human PAN2 Polyclonal Antibody | anti-PAN2 antibody
PAN2 Antibody, HRP conjugated
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Uniprot Description
USP52: Functions in cytoplasmic mRNA decay. As part of the Pan nuclease complex, shortens poly(A) tails of RNA when the poly(A) stretch is bound by polyadenylate-binding protein. Belongs to the peptidase C19 family. PAN2 subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Ribonuclease; Ubiquitin-specific protease; EC 3.1.13.4
Chromosomal Location of Human Ortholog: 12q13.2
Cellular Component: cytosol
Molecular Function: 3'-5'-exoribonuclease activity; poly(A)-specific ribonuclease activity; protein binding
Biological Process: poly(A) tail shortening
Research Articles on PAN2
Similar Products
Product Notes
The PAN2 pan2 (Catalog #AAA7045228) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PAN2 Antibody, HRP conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PAN2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the PAN2 pan2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
