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Rabbit anti-Human PAG1 Polyclonal Antibody | anti-PAG1 antibody

PAG1 Antibody, HRP conjugated

Gene Names
PAG1; CBP; PAG
Reactivity
Human
Applications
ELISA
Purity
>95%, Protein G purified
Synonyms
PAG1; Polyclonal Antibody; PAG1 Antibody; HRP conjugated; Phosphoprotein associated with glycosphingolipid-enriched microdomains 1; Csk-binding protein; Transmembrane adapter protein PAG; Transmembrane phosphoprotein Cbp; CBP; PAG; anti-PAG1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
432
Applicable Applications for anti-PAG1 antibody
ELISA (EIA)
Species
Human
Immunogen
Recombinant human Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 protein
Conjugate
HRP
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-11667 / sc-25748
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-PAG1 antibody
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,981 Da
NCBI Official Full Name
phosphoprotein associated with glycosphingolipid-enriched microdomains 1
NCBI Official Synonym Full Names
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
NCBI Official Symbol
PAG1
NCBI Official Synonym Symbols
CBP; PAG
NCBI Protein Information
phosphoprotein associated with glycosphingolipid-enriched microdomains 1
UniProt Protein Name
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1
Protein Family
UniProt Gene Name
PAG1
UniProt Synonym Gene Names
CBP; PAG
UniProt Entry Name
PHAG1_HUMAN

NCBI Description

The protein encoded by this gene is a type III transmembrane adaptor protein that binds to the tyrosine kinase csk protein. It is thought to be involved in the regulation of T cell activation. [provided by RefSeq, Jul 2008]

Uniprot Description

PAG: an ubiquitous type III transmembrane adaptor protein that binds to the tyrosine kinase CSK protein. It is thought to be involved in the regulation of T cell activation.

Protein type: Membrane protein, integral; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 8q21.13

Cellular Component: integral to plasma membrane; lipid raft; plasma membrane

Molecular Function: protein binding; SH2 domain binding; transmembrane receptor protein tyrosine kinase adaptor protein activity

Biological Process: epidermal growth factor receptor signaling pathway; negative regulation of T cell activation; regulation of T cell activation; signal transduction; T cell receptor signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway

Research Articles on PAG1

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Product Notes

The PAG1 pag1 (Catalog #AAA7044055) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PAG1 Antibody, HRP conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PAG1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the PAG1 pag1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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