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Immunohistochemistry (IHC) (Anti-PACSIN2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Rabbit PACSIN2 Polyclonal Antibody | anti-PACSIN2 antibody

Rabbit Polyclonal to Human PACSIN2

Gene Names
PACSIN2; SDPII
Reactivity
Bovine, Chimpanzee, Chicken, Dog, Xenopus, Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
PACSIN2; Polyclonal Antibody; Rabbit Polyclonal to Human PACSIN2; Anti-PACSIN2 Antibody (aa400-450) IHC-plus; SDPII; Syndapin II; Human PACSIN2; anti-PACSIN2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Bovine, Chimpanzee, Chicken, Dog, Xenopus, Human, Mouse, Rat
Clonality
Polyclonal
Specificity
A portion of amino acids 400-450 of human PACSIN2
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.2% gelatin, 0.05% sodium azide.
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
486
Applicable Applications for anti-PACSIN2 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes
IHC-P (10 ug/ml), WB (0.02 - 1 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Target Species
Human
Immunogen Description
Synthetic peptide from human PACSIN2.
Immunogen Type
Synthetic peptide
Immunogen
PACSIN2 antibody was raised against synthetic peptide from human PACSIN2.
Antigen Modification
aa400-450
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.

Immunohistochemistry (IHC)

(Anti-PACSIN2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC) (Anti-PACSIN2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Western Blot (WB)

(Western blot of PACSIN2 in human brain lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse brain lysate and 4) rat brain lysate using antibody at 0.05 ug/ml.)

Western Blot (WB) (Western blot of PACSIN2 in human brain lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse brain lysate and 4) rat brain lysate using antibody at 0.05 ug/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,353 Da
NCBI Official Full Name
protein kinase C and casein kinase substrate in neurons protein 2 isoform A
NCBI Official Synonym Full Names
protein kinase C and casein kinase substrate in neurons 2
NCBI Official Symbol
PACSIN2
NCBI Official Synonym Symbols
SDPII
NCBI Protein Information
protein kinase C and casein kinase substrate in neurons protein 2; syndapin2; syndapin 2; syndapin-2; syndapin II; syndapin-II; cytoplasmic phosphoprotein PACSIN2
UniProt Protein Name
Protein kinase C and casein kinase substrate in neurons protein 2
UniProt Gene Name
PACSIN2
UniProt Entry Name
PACN2_HUMAN

NCBI Description

This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

Uniprot Description

PACSIN2: May play a role in vesicle formation and transport. Belongs to the PACSIN family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 22q13.2-q13.33

Cellular Component: nucleoplasm; cytoplasmic vesicle membrane; extrinsic to membrane; focal adhesion; cytoskeleton; intracellular membrane-bound organelle; recycling endosome membrane; cytoplasm; early endosome; caveola; intercellular junction; cytosol

Molecular Function: identical protein binding; protein binding; transporter activity; cytoskeletal protein binding

Biological Process: negative regulation of endocytosis; regulation of endocytosis; cell projection morphogenesis; actin cytoskeleton organization and biogenesis

Research Articles on PACSIN2

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Product Notes

The PACSIN2 pacsin2 (Catalog #AAA241678) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human PACSIN2 reacts with Bovine, Chimpanzee, Chicken, Dog, Xenopus, Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PACSIN2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (10 ug/ml), WB (0.02 - 1 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the PACSIN2 pacsin2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PACSIN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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